| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A656369-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $227.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Biochemical and Physiological Mechanisms | ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC 50 value of 40 nM in cell. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC 50 value of 40 nM in cell In Vitro ALW-II-49-7 (compound 9) exhibits selectivity profile of binding to a set of kinases including b-raf, CSF1R, DDR1, DDR2, EphA2, EphA5, EphA8, EphB1, EphB2, EphB3, Frk, Kit, Lck, p38a, p38b, PDGFRa, PDGFRb, and Raf1. ALW-II-49-7 (0.01-10 μM; 1 h) inhibits EphB2 tyrosine kinase activity in U87 glioblastoma cells. EphB2 is added in media at 2 μg/mL. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:EphB2 |
| Canonical SMILES | O=C(C1=CC(NC2=CC(C(NC3=CC=CC(C(F)(F)F)=C3)=O)=CC=C2C)=CN=C1)N |
|---|---|
| Molecular Weight | 414.38 |
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