AM 114 - ≥97%(HPLC), high purity , CAS No.856849-35-9

Item Number

A287890

Grouped product items
SKU	Size	Availability	Price
A287890-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$59.90
A287890-10mg	10mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$98.90
A287890-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$197.90
A287890-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$345.90
A287890-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$573.90
A287890-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,291.90

20S proteasome inhibitor

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Basic Description

Specifications & Purity	≥97%(HPLC)
Biochemical and Physiological Mechanisms	Inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50~ 1μM). Displays anticancer activity; inhibits cell growth in human colon cancer HCT116 p53+/+ cells (IC50= 1.49μM).
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Names and Identifiers

IUPAC Name	[4-[(E)-[(5E)-5-[(4-boronophenyl)methylidene]-1-methyl-4-oxopiperidin-3-ylidene]methyl]phenyl]boronic acid
INCHI	InChI=1S/C20H21B2NO5/c1-23-12-16(10-14-2-6-18(7-3-14)21(25)26)20(24)17(13-23)11-15-4-8-19(9-5-15)22(27)28/h2-11,25-28H,12-13H2,1H3/b16-10+,17-11+
InChi Key	SRPIKXGUPAKTIZ-OTYYAQKOSA-N
Canonical SMILES	B(C1=CC=C(C=C1)C=C2CN(CC(=CC3=CC=C(C=C3)B(O)O)C2=O)C)(O)O
Isomeric SMILES	B(O)(O)C1=CC=C(C=C1)/C=C\2/C(=O)/C(=C/C3=CC=C(C=C3)B(O)O)/CN(C2)C
PubChem CID	11639443
Molecular Weight	377.01

Certificates

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6 results found

Lot Number	Certificate Type	Date	Item
E23151016	Certificate of Analysis	Mar 30, 2023	A287890
E23151017	Certificate of Analysis	Mar 30, 2023	A287890
E23151018	Certificate of Analysis	Mar 30, 2023	A287890
E2315975	Certificate of Analysis	Mar 30, 2023	A287890
E2315984	Certificate of Analysis	Mar 30, 2023	A287890
E2315985	Certificate of Analysis	Mar 30, 2023	A287890

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Basic Description