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AM-1473 , CAS No.A607575, Channel blocker of TRPC6

  • Moligand™
Item Number
A607575
Grouped product items
SKUSizeAvailabilityPrice Qty
A607575-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
A607575-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
View related series
TRPC6 Channel blocker

Basic Description

SynonymsAM1473
GradeMoligand™
Action TypeCHANNEL BLOCKER
Mechanism of actionChannel blocker of TRPC6

Associated Targets

TRPC6 Tchem Short transient receptor potential channel 6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 4-{[(1R,2S)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy}benzonitrile
INCHI InChI=1S/C21H23N3O/c22-13-15-7-9-18(10-8-15)25-21-19-6-2-1-4-16(19)12-20(21)24-11-3-5-17(23)14-24/h1-2,4,6-10,17,20-21H,3,5,11-12,14,23H2/t17-,20+,21-/m1/s1
InChi Key IVKKIBLLVHIRDV-JRGCBEDISA-N
Canonical SMILES N[C@@H]1CCCN(C1)[C@H]2CC3=C(C=CC=C3)[C@H]2OC4=CC=C(C=C4)C#N

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Bai Y, Yu X, Chen H, Horne D, White R, Wu X, Lee P, Gu Y, Ghimire-Rijal S, Lin DC et al..  (2020)  Structural basis for pharmacological modulation of the TRPC6 channel..  Elife,  (3): (589-97).  [PMID:32149605]

Solution Calculators