Click Here for 5% Off Your First Aladdin Purchase!

AM237 , CAS No.A607580, Activator of TRPC5

  • Moligand™
Item Number
A607580
Grouped product items
SKUSizeAvailabilityPrice Qty
A607580-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
A607580-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
View related series
TRPC5 Activator

Basic Description

SynonymsExample 319 [WO2014143799]
GradeMoligand™
Action TypeACTIVATOR
Mechanism of actionActivator of TRPC5

Associated Targets

TRPC5 Tchem Short transient receptor potential channel 5 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 7-[(4-chlorophenyl)methyl]-8-[4-chloro-3-(trifluoromethoxy)phenoxy]-1-(3-hydroxypropyl)-3-methylpurine-2,6-dione
INCHI InChI=1S/C23H19Cl2F3N4O5/c1-30-19-18(20(34)31(22(30)35)9-2-10-33)32(12-13-3-5-14(24)6-4-13)21(29-19)36-15-7-8-16(25)17(11-15)37-23(26,27)28/h3-8,11,33H,2,9-10,12H2,1H3
InChi Key UNQYAAAWKOOBFQ-UHFFFAOYSA-N
Canonical SMILES OCCCn1c(=O)c2n(Cc3ccc(cc3)Cl)c(nc2n(c1=O)C)Oc1ccc(c(c1)OC(F)(F)F)Cl
Isomeric SMILES CN1C2=C(C(=O)N(C1=O)CCCO)N(C(=N2)OC3=CC(=C(C=C3)Cl)OC(F)(F)F)CC4=CC=C(C=C4)Cl
PubChem CID 90403462

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

References

1. Minard A, Bauer CC, Chuntharpursat-Bon E, Pickles IB, Wright DJ, Ludlow MJ, Burnham MP, Warriner SL, Beech DJ, Muraki K et al..  (2019)  Potent, selective, and subunit-dependent activation of TRPC5 channels by a xanthine derivative..  Br J Pharmacol,  176  (20): (3924-3938).  [PMID:31277085]

Solution Calculators