AM966 - ≥98%, high purity , CAS No.1228690-19-4, Antagonist of LPA 1 receptor;Antagonist of LPA 2 receptor;Antagonist of LPA 3 receptor;Antagonist of LPA 4 receptor

Item Number

A125594

• Synonyms: 1228690-19-4|AM966|AM-966|(R)-2-(4'-(4-(((1-(2-Chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetic acid|UNII-CEO54NH393|CEO54NH393|[1,1'-Biphenyl]-4-acetic acid, 4'-[4-[[[(1R)-1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-m
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms:

  AM966 is a high affinity, selective, oral LPA1 (lysophosphatidic acid receptor) antagonist, with selectivity for this receptor over the other LPA receptors. In vitro, AM966 inhibited LPA-stimulated intracellular calcium release (IC(50)= 1

• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: ANTAGONIST
• Mechanism of action: Antagonist of LPA 1 receptor;Antagonist of LPA 2 receptor;Antagonist of LPA 3 receptor;Antagonist of LPA 4 receptor

Product Description

AM966 is a high affinity, selective, oral LPA1 (lysophosphatidic acid receptor, IC50=17 nM) antagonist, with selectivity for this receptor over the other LPA receptors.