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AMD 3465 hexahydrobromide - ≥97%, high purity , CAS No.185991-07-5

Specifications & Purity:  ≥97%
Item Number
A274943
Grouped product items
SKUSizeAvailabilityPrice Qty
A274943-2mg
2mg
In stock
$28.90
A274943-5mg
5mg
In stock
$59.90
A274943-10mg
10mg
In stock
$86.90
A274943-25mg
25mg
In stock
$195.90
A274943-50mg
50mg
In stock
$282.90
A274943-100mg
100mg
In stock
$521.90
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Discover AMD 3465 hexahydrobromide by Aladdin Scientific in ≥97% for only $28.90. Available - in Ligands at Aladdin Scientific. Potent and selective CXCR4 antagonist Tags: .

Basic Description

SynonymsN-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanaminehexahydrobromide；GENZ-644494 hexahydrobromide
Specifications & Purity≥97%
Storage TempStore at -20°C,Desiccated
Shipped InDry ice

Names and Identifiers

IUPAC Name N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine;hexahydrobromide
INCHI InChI=1S/C24H38N6.6BrH/c1-2-13-29-24(5-1)20-28-19-22-6-8-23(9-7-22)21-30-17-4-12-26-15-14-25-10-3-11-27-16-18-30;;;;;;/h1-2,5-9,13,25-28H,3-4,10-12,14-21H2;6*1H
InChi Key ARHBIBDGWDRBJH-UHFFFAOYSA-N
Canonical SMILES C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3.Br.Br.Br.Br.Br.Br
Isomeric SMILES C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3.Br.Br.Br.Br.Br.Br
Alternate CAS 185991-24-6
PubChem CID 9897616
Molecular Weight 896.07

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot NumberCertificate TypeDateItem
B2307090Certificate of AnalysisNov 14, 2023 A274943
B2307085Certificate of AnalysisNov 14, 2023 A274943
B2307084Certificate of AnalysisNov 14, 2023 A274943
B2307097Certificate of AnalysisNov 14, 2023 A274943
B2307081Certificate of AnalysisNov 14, 2023 A274943
B2307020Certificate of AnalysisNov 14, 2023 A274943

Chemical and Physical Properties

SolubilitySoluble in water to 50 mM and in DMSO to 25 mM
SensitivityMoisture sensitive

Safety and Hazards(GHS)

RIDADR NONHforallmodesoftransport

Related Documents

 SDS

 Specification Sheet

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References

1. Hatse S et al..  (2005)  AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor..  Biochem Pharmacol,  70  (5): (752-61).  [PMID:16011832]
2. Hu JS et al..  (2006)  AMD3465, a novel CXCR4 receptor antagonist, abrogates schistosomal antigen-elicited (type-2) pulmonary granuloma formation..  Am J Pathol,  169  (2): (424-32).  [PMID:16877345]
3. Bodart V et al..  (2009)  Pharmacology of AMD3465: a small molecule antagonist of the chemokine receptor CXCR4..  Biochem Pharmacol,  78  (8): (993-1000).  [PMID:19540208]
4. Forte D et al..  (2017)  The tissue inhibitor of metalloproteinases-1 (TIMP-1) promotes survival and migration of acute myeloid leukemia cells through CD63/PI3K/Akt/p21 signaling..  Oncotarget,  8  (2): (2261-2274).  [PMID:27903985]

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