| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A475616-500mg | 500mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,121.90 |
| Specifications & Purity | PEG average Mₙ 5,000, PCL average Mₙ 5,000 |
|---|---|
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Description Amine-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEGblockand a hydrophobic PCLblock. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The amine functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery. |
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| 1. Xiaoqiang Yang, Wenjing Deng, Liwu Fu, Elvin Blanco, Jinming Gao, Daping Quan, Xintao Shuai,. (2007-10-18) Folate-functionalized polymeric micelles for tumor targeted delivery of a potent multidrug-resistance modulator FG020326.. Journal of biomedical materials research. Part A, 86 ((1)): ( 48-60 ). [PMID:17941015] |
