Aminohexylgeldanamycin - 99%, high purity , CAS No.485395-71-9

  • ≥99%
Item Number
A648712
Grouped product items
SKUSizeAvailabilityPrice Qty
A648712-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$300.90
A648712-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$480.90
A648712-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$950.90

Basic Description

Specifications & Purity≥99%
Biochemical and Physiological MechanismsAminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities.
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
Product Description

Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities

In Vitro

HPMA copolymer-aminohexylgeldanamycin conjugates target cell surface expressed GRP78 in prostate cancer. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:HSP90

Names and Identifiers

IUPAC Name [(4Z,6Z,10Z)-19-(6-aminohexylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
INCHI InChI=1S/C34H52N4O8/c1-20-16-24-29(37-15-10-8-7-9-14-35)26(39)19-25(31(24)41)38-33(42)21(2)12-11-13-27(44-5)32(46-34(36)43)23(4)18-22(3)30(40)28(17-20)45-6/h11-13,18-20,22,27-28,30,32,37,40H,7-10,14-17,35H2,1-6H3,(H2,36,43)(H,38,42)/b13-11-,21-12-,23-18-
InChi Key FEKZHEHNADINKB-YIAZIGALSA-N
Canonical SMILES CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCCCCCN)C)OC)OC(=O)N)C)C)O)OC
PubChem CID 167995159
Molecular Weight 644.80

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 110 mg/mL (170.60 mM; Need ultrasonic)

Related Documents

Solution Calculators