| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A755563-10vials | 10vials | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $77.90 |
| Specifications & Purity | γ-irradiated, BioReagent, suitable for hybridoma, 50 ×, lyophilized powder |
|---|---|
| Biochemical and Physiological Mechanisms | Folic acid antagonist. Aminopterin is actively transported into cells by the folate transporter. In the cell, it is converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase that, in turn, binds to dihydrofolate reduct |
| Storage Temp | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Grade | BioReagent, suitable for hybridoma, γ-irradiated |
| Product Description | Aminopterin concentrate supplement for hybridoma cell culture applications. |
| IUPAC Name | (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid |
|---|---|
| INCHI | InChI=1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)/t12-/m0/s1 |
| InChi Key | TVZGACDUOSZQKY-LBPRGKRZSA-N |
| Canonical SMILES | C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N |
| Isomeric SMILES | C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N |
| WGK Germany | 3 |
| RTECS | MA1050000 |
| PubChem CID | 169371 |
| UN Number | 2811 |
| Packing Group | I |
| Molecular Weight | 440.41(as Anhydrous) |
| Beilstein | 69045 |
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| Solubility | 10 mL/vial, clear, red (in TC Medium) |
|---|---|
| Specific Rotation[α] | 20° (C=1,0.1mol/L NaOH) |
| Melt Point(°C) | 185-204°C |
| Pictogram(s) | GHS06, GHS08 |
|---|---|
| Signal | Danger |
| Hazard Statements | H300:Fatal if swallowed H360:May damage fertility or the unborn child |
| Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. |
| WGK Germany | 3 |
| RTECS | MA1050000 |
| Class | 6.1 |
| Merck Index | 472 |
