Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
A105056-25g | 25g | In stock | $15.90 | |
A105056-100g | 100g | In stock | $54.90 | |
A105056-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $59.90 |
Synonyms | SEMICARBAZIDE HYDROCHLORIDE|563-41-7|Aminourea hydrochloride|Semicarbazide HCl|hydrazinecarboxamide hydrochloride|Hydrazinecarboxamide, monohydrochloride|Semicarbazide chloride|Amidourea hydrochloride|Carbamylhydrazine hydrochloride|Hydrazinecarboxamide m |
---|---|
Specifications & Purity | ≥99% |
Shipped In | Normal |
Product Description | It is a metabolite of Nitrofuran. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Pubchem Sid | 488181289 |
---|---|
Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488181289 |
IUPAC Name | aminourea;hydrochloride |
INCHI | InChI=1S/CH5N3O.ClH/c2-1(5)4-3;/h3H2,(H3,2,4,5);1H |
InChi Key | XHQYBDSXTDXSHY-UHFFFAOYSA-N |
Canonical SMILES | C(=O)(N)NN.Cl |
Isomeric SMILES | C(=O)(N)NN.Cl |
WGK Germany | 3 |
RTECS | VT3500000 |
PubChem CID | 11236 |
UN Number | 2811 |
Packing Group | I |
Molecular Weight | 111.53 |
Beilstein | 3593642 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
B2322248 | Certificate of Analysis | Feb 27, 2023 | A105056 |
B2307096 | Certificate of Analysis | Feb 18, 2023 | A105056 |
K2226297 | Certificate of Analysis | Sep 28, 2022 | A105056 |
A2417113 | Certificate of Analysis | Sep 28, 2022 | A105056 |
K2226296 | Certificate of Analysis | Sep 28, 2022 | A105056 |
K2226295 | Certificate of Analysis | Sep 28, 2022 | A105056 |
K2226294 | Certificate of Analysis | Sep 28, 2022 | A105056 |
K2226127 | Certificate of Analysis | Sep 28, 2022 | A105056 |
K2226126 | Certificate of Analysis | Sep 28, 2022 | A105056 |
K2226125 | Certificate of Analysis | Sep 28, 2022 | A105056 |
K2226124 | Certificate of Analysis | Sep 28, 2022 | A105056 |
E2310737 | Certificate of Analysis | Sep 28, 2022 | A105056 |
I2223337 | Certificate of Analysis | May 31, 2022 | A105056 |
G2222047 | Certificate of Analysis | May 31, 2022 | A105056 |
G2222046 | Certificate of Analysis | May 31, 2022 | A105056 |
G2222045 | Certificate of Analysis | May 31, 2022 | A105056 |
D2419031 | Certificate of Analysis | May 31, 2022 | A105056 |
Solubility | Solubility in water: 100 g/L (15°C) Solubility in other solvents: insoluble in absolute alcohol and ether |
---|---|
Sensitivity | Moisture sensitive. |
Melt Point(°C) | 173-177°C |
Pictogram(s) | GHS06, GHS08, GHS07 |
---|---|
Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H301:Toxic if swallowed H373:Causes damage to organs through prolonged or repeated exposure H361:Suspected of damaging fertility or the unborn child |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | VT3500000 |
Class | 6.1 |
Merck Index | 8444 |
1. Phedias Diamandis,Jan Wildenhain,Ian D Clarke,Adrian G Sacher,Jeremy Graham,David S Bellows,Erick K M Ling,Ryan J Ward,Leanne G Jamieson,Mike Tyers,Peter B Dirks. (2007-04-10) Chemical genetics reveals a complex functional ground state of neural stem cells.. Nature chemical biology, 3 ((5)): (268-273). [PMID:17417631] |
2. Justin G Bendall. (2009-08-15) Semicarbazide is non-specific as a marker metabolite to reveal nitrofurazone abuse as it can form under Hofmann conditions.. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 26 ((1)): (47-56). [PMID:19680870] |
3. Z Iffiú-Soltész,E Wanecq,D Prévot,S Grès,C Carpéné. (2009-12-17) Histamine oxidation in mouse adipose tissue is controlled by the AOC3 gene-encoded amine oxidase.. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 59 Suppl 2 (S227-S229). [PMID:20012150] |
4. Jainendra Jain,Y Kumar,James Stables,Reema Sinha. (2010-04-21) Menthone semicarbazides and thiosemicarbazides as anticonvulsant agents.. Medicinal chemistry (Shariqah (United Arab Emirates)), 6 ((1)): (44-50). [PMID:20402660] |
5. Miwa Takahashi,Midori Yoshida,Kaoru Inoue,Tomomi Morikawa,Akiyoshi Nishikawa. (2010-05-08) Age-related susceptibility to induction of osteochondral and vascular lesions by semicarbazide hydrochloride in rats.. Toxicologic pathology, 38 ((4)): (598-605). [PMID:20448083] |
6. Qingyi Ma,Anatol Manaenko,Nikan H Khatibi,Wanqiu Chen,John H Zhang,Jiping Tang. (2010-09-30) Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 31 ((3)): (881-893). [PMID:20877383] |
7. Josep Mercader,Zsuzsa Iffiú-Soltesz,Xavier Brenachot,Agota Földi,Petra Dunkel,Balázs Balogh,Camille Attané,Philippe Valet,Péter Mátyus,Christian Carpéné. (2011-03-25) SSAO substrates exhibiting insulin-like effects in adipocytes as a promising treatment option for metabolic disorders.. Future medicinal chemistry, 2 ((12)): (1735-1749). [PMID:21428797] |
8. Kazimiera Cwiek-Ludwicka. (2010-01-01) [Hazards for health related to migration of substances from packaging into food].. Roczniki Panstwowego Zakladu Higieny, 61 ((4)): (341-347). [PMID:21446113] |
9. Yuping Chen,Gary L Skiles,Magang Shou,Dean Hickman,Faye Hsieh. (2011-06-16) A novel biotransformation of alkyl aminopyrrolidine to aminopiperidine ring by human CYP3A.. Drug metabolism and disposition: the biological fate of chemicals, 39 ((9)): (1668-1673). [PMID:21673127] |
10. Joshua A Obaleye,Johnson F Adediji,Matthew A Adebayo. (2011-07-14) Synthesis and biological activities on metal complexes of 2,5-diamino-1,3,4-thiadiazole derived from semicarbazide hydrochloride.. Molecules (Basel, Switzerland), 16 ((7)): (5861-5874). [PMID:21750479] |
11. Jing Ye,Xiang-Hong Wang,Ya-Xin Sang,Qian Liu. (2011-07-27) Assessment of the determination of azodicarbonamide and its decomposition product semicarbazide: investigation of variation in flour and flour products.. Journal of agricultural and food chemistry, 59 ((17)): (9313-9318). [PMID:21786817] |
12. Gongjun Yang,Wenjie Jin,Liping Wu,Qianqian Wang,Hongxia Shao,Aijian Qin,Bing Yu,Dongming Li,Baoliang Cai. (2011-10-15) Development of an impedimetric immunosensor for the determination of 3-amino-2-oxazolidone residue in food samples.. Analytica chimica acta, 706 ((1)): (120-127). [PMID:21995918] |
13. I Perković,I Butula,M Kralj,I Martin-Kleiner,J Balzarini,D Hadjipavlou-Litina,A-M Katsori,B Zorc. (2012-03-13) Novel NSAID 1-acyl-4-cycloalkyl/arylsemicarbazides and 1-acyl-5-benzyloxy/hydroxy carbamoylcarbazides as potential anticancer agents and antioxidants.. European journal of medicinal chemistry, 51 (227-238). [PMID:22405290] |
14. Haejung An,Mark Henry,Teresa Cain,Bichsa Tran,Han Chol Paek,Dennis Farley. (2012-09-14) Determination of total nitrofuran metabolites in shrimp muscle using liquid chromatography/tandem mass spectrometry in the atmospheric pressure chemical ionization mode.. Journal of AOAC International, 95 ((4)): (1222-1233). [PMID:22970594] |
15. Robert McCracken,Bob Hanna,David Ennis,Lynne Cantley,Dermot Faulkner,D Glenn Kennedy. (2012-12-01) The occurrence of semicarbazide in the meat and shell of Bangladeshi fresh-water shrimp.. Food chemistry, 136 ((3-4)): (1562-1567). [PMID:23194563] |
16. Grant Abernethy,Kerianne Higgs. (2013-04-02) Rapid detection of economic adulterants in fresh milk by liquid chromatography-tandem mass spectrometry.. Journal of chromatography. A, 1288 (10-20). [PMID:23540766] |
17. Yunfei Xie,Pei Li,Jin Zhang,Heya Wang,He Qian,Weirong Yao. (2013-06-12) Comparative studies by IR, Raman, and surface-enhanced Raman spectroscopy of azodicarbonamide, biurea and semicarbazide hydrochloride.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 114 (80-84). [PMID:23751223] |
18. Lesley Johnston,Meg Croft,John Murby. (2015-04-12) Fortified versus incurred residues: extraction of furazolidinone metabolite from prawn.. Analytical and bioanalytical chemistry, 407 ((16)): (4535-4540). [PMID:25862475] |
19. Haejung An,Lenin Parrales,Kai Wang,Teresa Cain,Ralph Hollins,Douglas Forrest,Benjamin Liao,Han Chol Paek,Jacqueline Sram. (2015-05-31) Quantitative Analysis of Nitrofuran Metabolites and Chloramphenicol in Shrimp Using Acetonitrile Extraction and Liquid Chromatograph-Tandem Mass Spectrometric Detection: A Single Laboratory Validation.. Journal of AOAC International, 98 ((3)): (602-608). [PMID:26025834] |
20. Shuai Zhang,Yuanming Guo,Zhongyong Yan,Xiumei Sun,Xiaojun Zhang. (2015-10-03) A selective biomarker for confirming nitrofurazone residues in crab and shrimp using ultra-performance liquid chromatography-tandem mass spectrometry.. Analytical and bioanalytical chemistry, 407 ((30)): (8971-8977). [PMID:26427505] |
21. Sabrina Zimdars,Lukas Schrage,Stephan Sommer,Andreas Schieber,Fabian Weber. (2019-09-19) Influence of Glutathione on Yeast Fermentation Efficiency under Copper Stress.. Journal of agricultural and food chemistry, 67 ((39)): (10913-10920). [PMID:31532663] |
22. Mikail E Abbasov,Madeline E Kavanagh,Taka-Aki Ichu,Michael R Lazear,Yongfeng Tao,Vincent M Crowley,Christopher W Am Ende,Stephan M Hacker,Jordan Ho,Melissa M Dix,Radu Suciu,Matthew M Hayward,Laura L Kiessling,Benjamin F Cravatt. (2021-09-11) A proteome-wide atlas of lysine-reactive chemistry.. Nature chemistry, 13 ((11)): (1081-1092). [PMID:34504315] |
23. Janaina M Zanoveli,Milene C Carvalho,Joice M Cunha,Marcus L Brandão. (2009-08-04) Extracellular serotonin level in the basolateral nucleus of the amygdala and dorsal periaqueductal gray under unconditioned and conditioned fear states: an in vivo microdialysis study.. Brain research, 1294 (106-115). [PMID:19646971] |
24. Francesca Maranghi,Roberta Tassinari,Daniele Marcoccia,Ilaria Altieri,Tiziana Catone,Giovanna De Angelis,Emanuela Testai,Sabina Mastrangelo,Maria Grazia Evandri,Paola Bolle,Stefano Lorenzetti. (2009-10-01) The food contaminant semicarbazide acts as an endocrine disrupter: Evidence from an integrated in vivo/in vitro approach.. Chemico-biological interactions, 183 ((1)): (40-48). [PMID:19788891] |
25. Fumiko Marttila-Ichihara,Karolien Castermans,Kaisa Auvinen,Mirjam G A Oude Egbrink,Sirpa Jalkanen,Arjan W Griffioen,Marko Salmi. (2010-02-16) Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice.. Journal of immunology (Baltimore, Md. : 1950), 184 ((6)): (3164-3173). [PMID:20154208] |
26. N Raman,A Selvan,P Manisankar. (2010-04-07) Spectral, magnetic, biocidal screening, DNA binding and photocleavage studies of mononuclear Cu(II) and Zn(II) metal complexes of tricoordinate heterocyclic Schiff base ligands of pyrazolone and semicarbazide/thiosemicarbazide based derivatives.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 76 ((2)): (161-173). [PMID:20363662] |
27. Wei Yang,Hui Li,Hongjun Luo,Wenhong Luo. (2010-12-15) Inhibition of semicarbazide-sensitive amine oxidase attenuates myocardial ischemia-reperfusion injury in an in vivo rat model.. Life sciences, 88 ((7-8)): (302-306). [PMID:21146547] |
28. B Kerkaert,F Mestdagh,B De Meulenaer. (2011-05-05) Formation of semicarbazide upon hypochlorous acid treatment of nitrogen containing compounds.. Communications in agricultural and applied biological sciences, 76 ((1)): (115-118). [PMID:21539211] |
29. Ramya K Kumar,Emma S Darios,Robert Burnett,Janice M Thompson,Stephanie W Watts. (2018-09-07) Fenfluramine-induced PVAT-dependent contraction depends on norepinephrine and not serotonin.. Pharmacological research, 140 (43-49). [PMID:30189295] |
30. Jaroslav Jenčo,Lenka Kujovská Krčmová,Luboš Sobotka,Vladimír Bláha,Petr Solich,František Švec. (2020-02-20) Development of novel liquid chromatography method for clinical monitoring of vitamin B1 metabolites and B6 status in the whole blood.. Talanta, 211 (120702-120702). [PMID:32070596] |
31. Cho-Han Chiang,Yen-Ling Lai,Yu-Ning Huang,Chun-Chiao Yu,Christine C Lu,Guann-Yi Yu,Ming-Jiun Yu. (2020-07-24) Sequential Phosphorylation of the Hepatitis C Virus NS5A Protein Depends on NS3-Mediated Autocleavage between NS3 and NS4A.. Journal of virology, 94 ((19)): [PMID:32699091] |