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AMP PNP - ≥90%(HPLC), high purity , CAS No.72957-42-7
Kir6 blocker; non-hydrolyzable AMP analog
Basic Description Synonyms AMP PNP | PD080102 | tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-(phosphonatoamino)phosphinate | AMP-PNP (tetralithium) | Adenylyl-imidodiphosphate,tetralithium salt | EINECS 277-127-5 | Adenosin Specifications & Purity ≥90%(HPLC) Biochemical and Physiological Mechanisms Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules. Storage Temp Store at -20°C Shipped In Ice chest + Ice pads
Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-(phosphonatoamino)phosphinate INCHI InChI=1S/C10H17N6O12P3.4Li/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21;;;;/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1 InChi Key FDBDJIGGLGUOPP-KWIZKVQNSA-J Canonical SMILES [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)(NP(=O)([O-])[O-])[O-])O)O)N Isomeric SMILES [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)(NP(=O)([O-])[O-])[O-])O)O)N Alternate CAS 25612-73-1； PubChem CID 10196276 Molecular Weight 506.20 (free acid basis)
Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: 26.5, Max Conc. mM: 50
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J2326021