Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
A125747-25mg | 25mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $46.90 | |
A125747-100mg | 100mg | In stock | $155.90 | |
A125747-500mg | 500mg | In stock | $702.90 | |
A125747-1g | 1g | In stock | $1,263.90 |
Synonyms | Ampalex|154235-83-3|piperidin-1-yl(quinoxalin-6-yl)methanone|CX516|CX-516|BDP 12|1-(quinoxalin-6-ylcarbonyl)piperidine|1-(6-Quinoxalinylcarbonyl)piperidine|BDP-12|CX 516|Piperidine, 1-(6-quinoxalinylcarbonyl)-|6-(piperidine-1-carbonyl)quinoxaline|173047-7 |
---|---|
Specifications & Purity | Moligand™, ≥95% |
Biochemical and Physiological Mechanisms | Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). IC50 value: Target: AMPA receptor A |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ALLOSTERIC MODULATOR |
Mechanism of action | Allosteric modulator of GluA1;Allosteric modulator of GluA2;Allosteric modulator of GluA3;Allosteric modulator of GluA4 |
Note | 500mg、25mg、100mg卖完停产,不再备货 |
Product Description | CX516 is a positive allosteric modulator at AMPA receptor that inhibits the deactivation of AMPA receptors. CX-516 is a nootropic and ampakine agent |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Pubchem Sid | 488188210 |
---|---|
Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488188210 |
IUPAC Name | piperidin-1-yl(quinoxalin-6-yl)methanone |
INCHI | InChI=1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2 |
InChi Key | ANDGGVOPIJEHOF-UHFFFAOYSA-N |
Canonical SMILES | C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2 |
Isomeric SMILES | C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2 |
RTECS | TM2785170 |
PubChem CID | 148184 |
Molecular Weight | 241.29 |
PubChem CID | 148184 |
---|---|
CAS Registry No. | 154235-83-3 |
ChEMBL Ligand | CHEMBL136800 |
Wikipedia | CX-516 |
RCSB PDB Ligand | CX5 |
PubChem SID | 488188210 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
K2211091 | Certificate of Analysis | Aug 22, 2024 | A125747 |
K2211093 | Certificate of Analysis | Aug 22, 2024 | A125747 |
K2211094 | Certificate of Analysis | Aug 22, 2024 | A125747 |
K2211095 | Certificate of Analysis | Aug 22, 2024 | A125747 |
C2302808 | Certificate of Analysis | Mar 14, 2023 | A125747 |
L2219133 | Certificate of Analysis | Jan 10, 2023 | A125747 |
L2219135 | Certificate of Analysis | Jan 10, 2023 | A125747 |
F1807031 | Certificate of Analysis | Feb 23, 2022 | A125747 |
Solubility | DMSO |
---|
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
RTECS | TM2785170 |