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Andrographiside - ≥95% (LC/MS-ELSD), high purity , CAS No.82209-76-5

Item Number
A463884
Grouped product items
SKUSizeAvailabilityPrice Qty
A463884-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$654.90

Basic Description

SynonymsAndrographoside|82209-76-5|(3E,4S)-3-[2-[(4aS,5R,6R,8aS)-6-hydroxy-5,8a-dimethyl-2-methylidene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one|AKOS0329
Specifications & Purity≥95% (LC/MS-ELSD)
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Description

Andrographiside is a labdane diterpenoid glucoside found in Andrographis paniculata, which is an annual herbaceous plant traditionally used to treat infections in Southern Asia.}

Names and Identifiers

IUPAC Name (3E,4S)-3-[2-[(4aS,5R,6R,8aS)-6-hydroxy-5,8a-dimethyl-2-methylidene-5-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one
INCHI InChI=1S/C26H40O10/c1-13-4-7-18-25(2,15(13)6-5-14-16(28)11-34-23(14)33)9-8-19(29)26(18,3)12-35-24-22(32)21(31)20(30)17(10-27)36-24/h5,15-22,24,27-32H,1,4,6-12H2,2-3H3/b14-5+/t15?,16-,17-,18+,19-,20-,21+,22-,24-,25+,26+/m1/s1
InChi Key VUEPOIYXKZTLMD-JXJPMOHRSA-N
Canonical SMILES CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)COC4C(C(C(C(O4)CO)O)O)O)O
Isomeric SMILES C[C@@]12CC[C@H]([C@@]([C@H]1CCC(=C)C2C/C=C/3\[C@@H](COC3=O)O)(C)CO[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O
PubChem CID 6439612
Molecular Weight 512.59

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Flash Point(°F)Not applicable
Flash Point(°C)Not applicable

Safety and Hazards(GHS)

RIDADR NONH for all modes of transport

Related Documents

References

1. W L Deng.  (1985-07-01)  [Pharmacological studies on thirteen kinds of injections from Andrographis paniculata. I. Antipyretic, anti-inflammatory effects and toxicity]..  Zhong yao tong bao (Beijing, China : 1981),  10  ((7)): (38-42).  [PMID:2932241]
2. C Q Hu,B N Zhou.  (1982-06-01)  [Isolation and structure of two new diterpenoid glucosides from Andrographis paniculata Nees]..  Yao xue xue bao = Acta pharmaceutica Sinica,  17  ((6)): (435-440).  [PMID:7148467]
3. Y Huang.  (2003-01-17)  [Comprehensive evaluation of cuanhuning injection]..  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica,  26  ((6)): (427-429).  [PMID:12528514]
4. A Kapil,I B Koul,S K Banerjee,B D Gupta.  (1993-07-06)  Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata..  Biochemical pharmacology,  46  ((1)): (182-185).  [PMID:8347130]
5. J Melchior,A A Spasov,O V Ostrovskij,A E Bulanov,G Wikman.  (2000-11-18)  Double-blind, placebo-controlled pilot and phase III study of activity of standardized Andrographis paniculata Herba Nees extract fixed combination (Kan jang) in the treatment of uncomplicated upper-respiratory tract infection..  Phytomedicine : international journal of phytotherapy and phytopharmacology,  ((5)): (341-350).  [PMID:11081985]
6. Jing Li,Li Luo,Xiaoyun Wang,Bin Liao,Guoping Li.  (2009-11-06)  Inhibition of NF-kappaB expression and allergen-induced airway inflammation in a mouse allergic asthma model by andrographolide..  Cellular & molecular immunology,  ((5)): (381-385).  [PMID:19887051]

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