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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A141501-10mg | 10mg | In stock | $23.90 | |
A141501-25mg | 25mg | In stock | $48.90 |
Synonyms | Angelicin|523-50-2|ISOPSORALEN|2H-Furo[2,3-H]chromen-2-one|furo[2,3-h]chromen-2-one|Angecin|2-Oxo-(2H)-furo(2,3-h)-1-benzopyran|Furo(2,3-h)coumarin|Isopsoralin|2H-Furo[2,3-H]-1-benzopyran-2-one|Angelicin (coumarin derivative)|Angelicin (coumarin deriv)|An |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Angular furocoumarin with diverse photobiological effects. Upon long-wavelength UV irradiation, forms monoadduct with double-stranded DNA and reacts with unsaturated fatty acids. Inhibits DNA and RNA synthesis and cell replication in Ehrlich ascites tumor |
Shipped In | Normal |
Note | 卖完停产,不再备货 |
Product Description | An angular furocoumarin, may be used as a photoactivatable molecule that reacts with DNA and unsaturated fatty acids to form monoadducts. Angelicin may be studied as a potential phototherapeutic and to understand its mechanisms of action and effects on RNA and DNA synthesis. |
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IUPAC Name | furo[2,3-h]chromen-2-one |
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INCHI | InChI=1S/C11H6O3/c12-10-4-2-7-1-3-9-8(5-6-13-9)11(7)14-10/h1-6H |
InChi Key | XDROKJSWHURZGO-UHFFFAOYSA-N |
Canonical SMILES | C1=CC2=C(C=CO2)C3=C1C=CC(=O)O3 |
Isomeric SMILES | C1=CC2=C(C=CO2)C3=C1C=CC(=O)O3 |
RTECS | LV0940000 |
PubChem CID | 10658 |
Molecular Weight | 186.16 |
Reaxy-Rn | 153970 |
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Lot Number | Certificate Type | Date | Item |
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D1713233 | Certificate of Analysis | Jul 12, 2024 | A141501 |
H2321404 | Certificate of Analysis | Aug 25, 2023 | A141501 |
H2321405 | Certificate of Analysis | Aug 25, 2023 | A141501 |
H2321406 | Certificate of Analysis | Aug 25, 2023 | A141501 |
H2321442 | Certificate of Analysis | Aug 25, 2023 | A141501 |
Solubility | Soluble in Chloroform and Methanol |
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Sensitivity | Heat sensitive |
Boil Point(°C) | 104 °C/4 mmHg |
Melt Point(°C) | 140 °C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H351:Suspected of causing cancer H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
RTECS | LV0940000 |
Reaxy-Rn | 153970 |