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Angelicin - ≥98%, high purity , CAS No.523-50-2

  • ≥98%
Item Number
A141501
Grouped product items
SKUSizeAvailabilityPrice Qty
A141501-10mg
10mg
In stock
$23.90
A141501-25mg
25mg
In stock
$48.90

Basic Description

SynonymsAngelicin|523-50-2|ISOPSORALEN|2H-Furo[2,3-H]chromen-2-one|furo[2,3-h]chromen-2-one|Angecin|2-Oxo-(2H)-furo(2,3-h)-1-benzopyran|Furo(2,3-h)coumarin|Isopsoralin|2H-Furo[2,3-H]-1-benzopyran-2-one|Angelicin (coumarin derivative)|Angelicin (coumarin deriv)|An
Specifications & Purity≥98%
Biochemical and Physiological MechanismsAngular furocoumarin with diverse photobiological effects. Upon long-wavelength UV irradiation, forms monoadduct with double-stranded DNA and reacts with unsaturated fatty acids. Inhibits DNA and RNA synthesis and cell replication in Ehrlich ascites tumor
Shipped InNormal
Note卖完停产,不再备货
Product Description

An angular furocoumarin, may be used as a photoactivatable molecule that reacts with DNA and unsaturated fatty acids to form monoadducts. Angelicin may be studied as a potential phototherapeutic and to understand its mechanisms of action and effects on RNA and DNA synthesis.

Associated Targets

SIRT1 Tchem NAD-dependent protein deacetylase sirtuin-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP1A1 Tchem Cytochrome P450 1A1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BACE1 Tchem Beta-secretase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ACHE Tclin Acetylcholinesterase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH3A1 Tchem Aldehyde dehydrogenase, dimeric NADP-preferring 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOB Tclin Amine oxidase [flavin-containing] B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAOA Tclin Amine oxidase [flavin-containing] A 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH2 Tclin Aldehyde dehydrogenase, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name furo[2,3-h]chromen-2-one
INCHI InChI=1S/C11H6O3/c12-10-4-2-7-1-3-9-8(5-6-13-9)11(7)14-10/h1-6H
InChi Key XDROKJSWHURZGO-UHFFFAOYSA-N
Canonical SMILES C1=CC2=C(C=CO2)C3=C1C=CC(=O)O3
Isomeric SMILES C1=CC2=C(C=CO2)C3=C1C=CC(=O)O3
RTECS LV0940000
PubChem CID 10658
Molecular Weight 186.16
Reaxy-Rn 153970

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

5 results found

Lot NumberCertificate TypeDateItem
D1713233Certificate of AnalysisJul 12, 2024 A141501
H2321404Certificate of AnalysisAug 25, 2023 A141501
H2321405Certificate of AnalysisAug 25, 2023 A141501
H2321406Certificate of AnalysisAug 25, 2023 A141501
H2321442Certificate of AnalysisAug 25, 2023 A141501

Chemical and Physical Properties

SolubilitySoluble in Chloroform and Methanol
SensitivityHeat sensitive
Boil Point(°C)104 °C/4 mmHg
Melt Point(°C)140 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H351:Suspected of causing cancer

H302:Harmful if swallowed

H312:Harmful in contact with skin

H332:Harmful if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

RTECS LV0940000
Reaxy-Rn 153970

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