| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A655627-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 |
| Specifications & Purity | 10mM in Water |
|---|---|
| Storage Temp | Protected from light,Desiccated,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Angiotensin II 5-valine is an agonist of angiotensin receptor . In Vivo By day 12, systolic blood pressure (SBP) increases significantly in Angiotensin II 5-valine infused rats (197±7 mm Hg).The development of hypertension in ANG II infused rats is prevented by losartan treatment. Blood and kidney samples are harvested, subjected to HPLC to separate Angiotensin II 5-valine (exogenous) from Ile5-ANG II (endogenous) and the fractions are measured by radioimmunoassay. In the Angiotensin II 5-valine infused rats treated with losartan, total plasma ANG II levels are elevated to a greater extent than in rats not treated with losartan (289±20 v 119±14 fmol/mL). However, losartan markedly decrease by 88% the enhancement of intrarenal Val5-ANG II content that occurred in the rats infused with Val5-ANG II alone . MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:Angiotensin receptor |
| Canonical SMILES | CC(C)C(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)C)C(=O)NC(CC2=CN=CN2)C(=O)N3CCCC3C(=O)NC(CC4=CC=CC=C4)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N |
|---|---|
| Molecular Weight | 1032.2 |
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