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Angiotensin II human Acetate - 98%, high purity , CAS No.68521-88-0

  • ≥98%
Item Number
A420049
Grouped product items
SKUSizeAvailabilityPrice Qty
A420049-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$32.90
A420049-10mg
10mg
In stock
$53.90
A420049-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$121.90
A420049-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$229.90
A420049-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$334.90
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Angiotensin Receptor Apoptosis

Basic Description

SynonymsAngiotensin II acetate [USAN] | ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT | Angiotensin II human acetate | Human angiotensin II acetate salt | Angiotensin II acetate human | Angiotensin II human (acetate) | Angiotensin II acetate | Angiotensin II aceta
Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Angiotensin II human (Angiotensin II) acetate is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human acetate plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human acetate stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human acetate induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis. Angiotensin II human acetate induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway

Names and Identifiers

IUPAC Name acetic acid;(3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
INCHI InChI=1S/C50H71N13O12.C2H4O2/c1-5-28(4)41(47(72)59-36(23-31-25-54-26-56-31)48(73)63-20-10-14-38(63)45(70)60-37(49(74)75)22-29-11-7-6-8-12-29)62-44(69)35(21-30-15-17-32(64)18-16-30)58-46(71)40(27(2)3)61-43(68)34(13-9-19-55-50(52)53)57-42(67)33(51)24-39(65)66;1-2(3)4/h6-8,11-12,15-18,25-28,33-38,40-41,64H,5,9-10,13-14,19-24,51H2,1-4H3,(H,54,56)(H,57,67)(H,58,71)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,65,66)(H,74,75)(H4,52,53,55);1H3,(H,3,4)/t28-,33-,34-,35-,36-,37-,38-,40-,41-;/m0./s1
InChi Key VBTZKFAHKJXHBA-PIONDTTLSA-N
Canonical SMILES CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N.CC(=O)O
Isomeric SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)O)N.CC(=O)O
PubChem CID 172197
Molecular Weight 1046.18(free base)

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeDateItem
H2422060Certificate of AnalysisJul 25, 2024 A420049
A2426166Certificate of AnalysisJan 17, 2024 A420049
A2426167Certificate of AnalysisJan 17, 2024 A420049
A2426168Certificate of AnalysisJan 17, 2024 A420049
A2426169Certificate of AnalysisJan 17, 2024 A420049
A2426170Certificate of AnalysisJan 17, 2024 A420049
I2221150Certificate of AnalysisJun 30, 2022 A420049
I2221158Certificate of AnalysisJun 30, 2022 A420049
I2221159Certificate of AnalysisJun 30, 2022 A420049
I2221160Certificate of AnalysisJun 30, 2022 A420049
I2221161Certificate of AnalysisJun 30, 2022 A420049

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Chemical and Physical Properties

SensitivityMoisture sensitive

Related Documents

 SDS

 Specification Sheet

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FAQs and Articles

FAQ
A New Role for Angiotensin II in Aging
Categories: Technical articles
Tags:
Alzheimer's disease Neuropeptide Angiotensin hypertensive

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