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ANO1-IN-1 , CAS No.407587-01-3

Item Number
A649830
Grouped product items
SKUSizeAvailabilityPrice Qty
A649830-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$50.90
A649830-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$70.90
A649830-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$145.90
A649830-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$230.90

Basic Description

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC 50 of 2.56 μM and 15.43 μM against ANO1 and ANO2 , respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells

In Vitro

ANO1-IN-1 (Compound 9c) (10 μM) significantly suppresses migration and invasion of U251 cells. ANO1-IN-1 and TMZ combination brings about remarkable synergistic effects in suppressing proliferation of GBM cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC 50 : 2.56 μM (ANO1), 15.43 μM (ANO2)

Names and Identifiers

Canonical SMILES CC(C)(C(NC1=C(C2=C(S1)CC(CC2)C(C)(C)C)C(N)=O)=O)C
Molecular Weight 336.49

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