Therapeutic Antibodies

Associated targets:  ERBB2

Cas#: 180288-69-1        Compound CID:  135518164

Formula:  C₆₄₇₀H₁₀₀₁₂N₁₇₂₆O₂₀₁₃S₄₂        Molecular Weight: 145531.50

IUPAC Name: 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

SMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O

InChIKey: FNXPTCITVCRFRK-UMMCILCDSA-N

InChI: InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1

Associated targets:  VEGFA

Cas#: 216974-75-3       

Formula:         Molecular Weight: 149 kDa(Average)

Associated targets:  ELANE PRTN3 TNF

Species reactivity(Reacts with):  Cynomolgus monkey,Human,Mouse,Rhesus monkey

Host species:  Human    Conjugation:  Unconjugated   

Cas#: 331731-18-1        Compound CID:  107706

IUPAC Name: 2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid

SMILES: CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O

InChIKey: BTGNGJJLZOIYID-UHFFFAOYSA-N

InChI: InChI=1S/C20H22N2O7S/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24)

Associated targets:  PCSK9

Cas#: 1245916-14-6       

SMILES: C(C(COP(=O)(O)O)O)O.[Na].[Na]

InChIKey: CATWCRUATKKAAQ-UHFFFAOYSA-N

InChI: InChI=1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;

Associated targets:  CD274

Species reactivity(Reacts with):  Human

Conjugation:  Unconjugated   

Cas#: 1380723-44-3        Compound CID:  168009942

SMILES: CC.CCCC(=NC(CC=C)C1=CC(=C(C=C1)N)S)C=C(C(=O)N(CCC(C)CC)C(C)CC)N.CC=CC(=CC)C(=O)C

Associated targets:  CD274

Species reactivity(Reacts with):  Cynomolgus monkey,Dog,Human,Mouse,Rabbit,Rat

Host species:  Human    Conjugation:  Unconjugated   

Cas#: 1537032-82-8        Compound CID:  168266339

IUPAC Name: 4-O-[2-(tert-butylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(cyclohexylmethylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(cyclohexylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(2,2-dimethylpropylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(ethylsulfonylamino)-2-phenylethyl] 1-O-methyl but-2-enedioate;4-O-[2-(methanesulfonamido)-2-phenylethyl] 1-O-methyl but-2-enedioate;1-O-methyl 4-O-[2-(2-methylpropylsulfonylamino)-2-phenylethyl] but-2-enedioate;1-O-methyl 4-O-[2-phenyl-2-(propan-2-ylsulfonylamino)ethyl] but-2-enedioate

SMILES: CCS(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)CS(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)S(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)(C)CS(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.CC(C)(C)S(=O)(=O)NC(COC(=O)C=CC(=O)OC)C1=CC=CC=C1.COC(=O)C=CC(=O)OCC(C1=CC=CC=C1)NS(=O)(=O)C.COC(=O)C=CC(=O)OCC(C1=CC=CC=C1)NS(=O)(=O)CC2CCCCC2.COC(=O)C=CC(=O)OCC(C1=CC=CC=C1)NS(=O)(=O)C2CCCCC2

InChIKey: YRKYEQYAGDIKGE-UHFFFAOYSA-N

InChI: InChI=1S/C20H27NO6S.C19H25NO6S.C18H25NO6S.2C17H23NO6S.C16H21NO6S.C15H19NO6S.C14H17NO6S/c1-26-19(22)12-13-20(23)27-14-18(17-10-6-3-7-11-17)21-28(24,25)15-16-8-4-2-5-9-16;1-25-18(21)12-13-19(22)26-14-17(15-8-4-2-5-9-15)20-27(23,24)16-10-6-3-7-11-16;1-18(2,3)13-26(22,23)19-15(14-8-6-5-7-9-14)12-25-17(21)11-10-16(20)24-4;1-17(2,3)25(21,22)18-14(13-8-6-5-7-9-13)12-24-16(20)11-10-15(19)23-4;1-13(2)12-25(21,22)18-15(14-7-5-4-6-8-14)11-24-17(20)10-9-16(19)23-3;1-12(2)24(20,21)17-14(13-7-5-4-6-8-13)11-23-16(19)10-9-15(18)22-3;1-3-23(19,20)16-13(12-7-5-4-6-8-12)11-22-15(18)10-9-14(17)21-2;1-20-13(16)8-9-14(17)21-10-12(15-22(2,18)19)11-6-4-3-5-7-11/h3,6-7,10-13,16,18,21H,2,4-5,8-9,14-15H2,1H3;2,4-5,8-9,12-13,16-17,20H,3,6-7,10-11,14H2,1H3;5-11,15,19H,12-13H2,1-4H3;5-11,14,18H,12H2,1-4H3;4-10,13,15,18H,11-12H2,1-3H3;4-10,12,14,17H,11H2,1-3H3;4-10,13,16H,3,11H2,1-2H3;3-9,12,15H,10H2,1-2H3

Associated targets:  PDCD1

Species reactivity(Reacts with):  Cynomolgus monkey,Human

Host species:  Human    Conjugation:  Unconjugated   

Cas#: 1798286-48-2       

Associated targets:  PDCD1

Species reactivity(Reacts with):  Human

Host species:  Human    Conjugation:  Unconjugated   

Cas#: 1801342-60-8       

Associated targets:  EGFR

Cas#: 205923-56-4       

Formula:         Molecular Weight: 145543.35

Associated targets:  CD38

Species reactivity(Reacts with):  Cynomolgus monkey,Human,Mouse,Rhesus monkey

Host species:  Human    Conjugation:  Unconjugated   

Cas#: 945721-28-8       

Associated targets:  CD274

Species reactivity(Reacts with):  Cynomolgus monkey,Human,Mouse

Host species:  Human    Conjugation:  Unconjugated   

Cas#: 1428935-60-7       

Associated targets:  TNF

Species reactivity(Reacts with):  Cynomolgus monkey,Human

Host species:  Human    Conjugation:  Unconjugated   

Cas#: 170277-31-3