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Antimycin A2 - ≥98%, high purity , CAS No.27220-57-1
a potent inhibitor of respiration with broad biological activity
Basic Description Synonyms Antimycin A2 | 27220-57-1 | UNII-ZIK247VR77 | EINECS 248-342-1 | [3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] butanoate | ZIK247VR77 | 3-(3-Formamidosalicylamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl butyrate | Specifications & Purity ≥98% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Antimycin A2 is a homologue of the antimycin complex, first resolved from antimycin A1 in 1959. Antimycin A2, like all antimycins, is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A2 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active. Lack of availability of the individual antimycin components has hindered greater understanding of the common and unique molecular targets of the components of the antimycin complex.
Names and Identifiers IUPAC Name [3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] butanoate INCHI InChI=1S/C27H38N2O9/c1-5-7-8-9-12-19-24(38-21(31)11-6-2)17(4)37-27(35)22(16(3)36-26(19)34)29-25(33)18-13-10-14-20(23(18)32)28-15-30/h10,13-17,19,22,24,32H,5-9,11-12H2,1-4H3,(H,28,30)(H,29,33) InChi Key LYDAGTPXPZARPR-UHFFFAOYSA-N Canonical SMILES CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CCC Isomeric SMILES CCCCCCC1C(C(OC(=O)C(C(OC1=O)C)NC(=O)C2=C(C(=CC=C2)NC=O)O)C)OC(=O)CCC PubChem CID 3084471 UN Number 2811 Packing Group II Molecular Weight 534.6
Chemical and Physical Properties Solubility Soluble in ethanol, methanol, DMF, DMSO, and water (poor). Refractive Index n20D1.55 (Predicted) Boil Point(°C) 756.37° C at 760 mmHg (Predicted)
Safety and Hazards(GHS) Pictogram(s) GHS06 Signal Danger Hazard Statements H301: Toxic if swallowed
H311: Toxic in contact with skin
H331: Toxic if inhaled
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P270: Do not eat, drink or smoke when using this product.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P330: Rinse mouth.
P361+P364: Take off immediately all contaminated clothing and wash it before reuse.
P301+P316: IF SWALLOWED: Get emergency medical help immediately.
P316: Get emergency medical help immediately.
Class 6.1
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