Arachis hypogaea lectin (PNA, Peanut Agglutinin)

Item Number

A140087

• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

Arachis hypogaea lectin or Peanut Agglutinin (PNA) is isolated from peanuts and purified by affinity chromatography. The lectin has a molecular weight of 110 kDa and consists of four identical subunits of approximately 27 kDa each. PNA is a carbohydrate-free protein that displays specificity towards ?-D-Gal(1-3)-D-galNAc. It has potent anti-T activity and can be used to distinguish between human lymphocyte subsets. PNA has been used in tumour tissue determination for transitional mucosa malignancies. The lectin also agglutinates neuraminidase-treated human erythrocytes at < 0.1 μg/ml after trypsin treatment of cells and its activity is inhibited by lactose and galactose. PNA lectin is provided as a white to light yellow lyophilized powder from a buffer containing 10 mM NH4HCO3. The purity is determined by SDS-PAGE, which generates one band at 25-27 kDa.
● Ultrapure quality
● Strong anti-T activity
● Sugar specificity: ?-D-Gal-(1-3)-D-GalNAc
● Agglutinates rabbit erythrocytes at < 0.1 μg/ml after trypsin treatment of the cells
● Lyophilized powder
Probe in histochemistry and immuno-histochemistry;Human erythrocyte/lymphocyte studies