ARD-2585 - 98%, high purity , CAS No.2757422-79-8

Item Number

A607716

Grouped product items
SKU	Size	Availability	Price
A607716-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$136.90
A607716-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$408.90
A607716-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$571.90
A607716-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$999.90

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Synonyms

ARD2585;compound 43

Specifications & Purity

Moligand™, ≥98%

Storage Temp

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Grade

Moligand™

Product Description

ARD-2585 is a potent PROTAC depressant for androgen receptors

Canonical SMILES

O=C(N(C1C(NC(CC1)=O)=O)C2=O)C(C2=C3)=CC=C3N(C4)CC4N(CC5)CCN5C(C=C6)=CC=C6C(N[C@@H]7CC[C@@H](N(C)C8=CC=C(C#N)C(Cl)=C8)CC7)=O

Molecular Weight

763.30

References

1. Xiang W, Zhao L, Han X, Qin C, Miao B, McEachern D, Wang Y, Metwally H, Kirchhoff PD, Wang L et al.. (2021) Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer.. J Med Chem, 64 (18): (13487-13509). [PMID:34473519]

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Basic Description