Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab177878-100μg | 100μg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $109.90 | |
| Ab177878-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $519.90 | |
| Ab177878-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,399.90 | |
| Ab177878-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,239.90 |
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | ASG-5ME (anti-SLC44A4) - Primary antibody, specific to SLC44A4, >95%, high purity, Human IgG2 |
|---|---|
| Synonyms | C6orf29 antibody; Choline transporter-like protein 4 antibody; CTL4 antibody; CTL4_HUMAN antibody; NG22 antibody; Slc44a4 antibody; Solute carrier family 44 member 4 antibody; UNQ441/PRO874 antibody |
| Specifications & Purity | ExactAb™, Validated, Carrier Free, Low Endotoxin, Azide Free, Recombinant, ≥95%(SDS-PAGE&SEC), Lot by Lot |
| Specificity | SLC44A4 |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | BINDING AGENT |
| Mechanism of action | BINDING AGENT of Choline transporter-like protein 4 binding agent |
| Product Description | ASG-5ME (anti-SLC44A4) is a fully human IgG2k monoclonal antibody targeting SLC44A4 (AGS-5) with potential antineoplastic activity. |
| Isotype | Human IgG2 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.3 kDa (Light Chain) & 51.5 kDa (Heavy Chain), under reducing conditions; 183.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Form | Liquid |
| Concentration | Lot by Lot |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
ASG-5ME (anti-SLC44A4) (Ab177878) - Flow Cytometry
pLVX-puro-SYMX01-ASG-5ME-FL cells were stained with ASG-5ME (anti-SLC44A4) (Ab177878) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, the EC50 is 23.94 nM.
ASG-5ME (anti-SLC44A4) (Ab177878) - SEC
The purity of ASG-5ME (anti-SLC44A4) (Ab177878) is more than 95% verified by HPLC.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0607181 | Certificate of Analysis | Jun 21, 2024 | Ab177878 |
| ZJ24F0607180 | Certificate of Analysis | Jun 21, 2024 | Ab177878 |
| ZJ24F0607179 | Certificate of Analysis | Jun 21, 2024 | Ab177878 |
| 1. O'Regan, S S and 5 more authors.. (2000) An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins.. Proceedings of the National Academy of Sciences of the United States of America, (15): [PMID:10677542] |
| 2. Uhl, Johannes J and 5 more authors.. (2002) Identification of a CTL4/Neu1 fusion transcript in a sialidosis patient.. FEBS letters, (19): [PMID:12067718] |
| 3. Xie, Tao T and 7 more authors.. (2003) Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.. Genome research, [PMID:14656967] |
| 4. Song, Pingfang P and 8 more authors.. (2013) Choline transporter-like protein 4 (CTL4) links to non-neuronal acetylcholine synthesis.. Journal of neurochemistry, [PMID:23651124] |
| 5. Nabokina, Svetlana M SM and 5 more authors.. (2014) Molecular identification and functional characterization of the human colonic thiamine pyrophosphate transporter.. The Journal of biological chemistry, (14): [PMID:24379411] |
| 6. Gupta, A A and Thelma, B K BK.. (2016) Identification of critical variants within SLC44A4, an ulcerative colitis susceptibility gene identified in a GWAS in north Indians.. Genes and immunity, [PMID:26741288] |
| 7. Nabokina, Svetlana M SM, Subramanian, Veedamali S VS and Said, Hamid M HM.. (2016) The human colonic thiamine pyrophosphate transporter (hTPPT) is a glycoprotein and N-linked glycosylation is important for its function.. Biochimica et biophysica acta, [PMID:26828122] |
| 8. Ma, Zhaoxin Z and 9 more authors.. (2017) SLC44A4 mutation causes autosomal dominant hereditary postlingual non-syndromic mid-frequency hearing loss.. Human molecular genetics, (15): [PMID:28013291] |
