ATWLPPR Peptide TFA - 99%, high purity , CAS No.A658822

  • ≥99%
Item Number
A658822
Grouped product items
SKUSizeAvailabilityPrice Qty
A658822-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$70.90

Basic Description

Specifications & Purity≥99%
Storage TempProtected from light,Desiccated,Store at -80°C
Shipped InIce chest + Ice pads
Product Description

ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF 165 binding to NRP-1, used in the research of angiogenesis. ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes .

Appearance:Solid

IC50& Target:Neuropilin-1

In Vitro:ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor, inhibits VEGF 165 binding to NRP-1 by 82% at 100 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo:ATWLPPR (400 μg/kg, s.c.) preserves vascular integrity and decreases the oxidative stress level, possibly reduces the early retinal damage caused by diabetes. ATWLPPR prevents the increase of inflammation-associated proteins (GFAP, VEGF and ICAM-1) i

Biological Activity:ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF 165 binding to NRP-1, used in the research of angiogenesis. ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes.

Names and Identifiers

Canonical SMILES O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(N4[C@@H](CCC4)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)[C@H](C)N.OC(C(F)(F)F)=O
Molecular Weight 954

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityH2O : ≥ 50 mg/mL (52.41 mM)

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Solution Calculators