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AZ13102909 , CAS No.A607833, Inhibitor of TANK binding kinase 1

Item Number

A607833

Grouped product items
SKU	Size	Availability	Price	Qty
A607833-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,000.90
A607833-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Synonyms	AZ909
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of TANK binding kinase 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	7-{2-[3-(cyclohexylformamido)propyl]hydrazin-1-yl}-2-{4'-methoxy-[1,1'-biphenyl]-4-yl}-2H,3H,3aH-imidazo[4,5-b]pyridine-6-carboxamide
INCHI	InChI=1S/C30H37N7O3/c1-40-23-14-12-20(13-15-23)19-8-10-21(11-9-19)28-35-26-25(24(27(31)38)18-33-29(26)36-28)37-34-17-5-16-32-30(39)22-6-3-2-4-7-22/h8-15,18,22,28-29,34,36-37H,2-7,16-17H2,1H3,(H2,31,38)(H,32,39)
InChi Key	UMLDEMVOMRDOLS-UHFFFAOYSA-N
Canonical SMILES	COc1ccc(cc1)c1ccc(cc1)C1NC2C(=N1)C(=C(C=N2)C(=O)N)NNCCCNC(=O)C1CCCCC1
PubChem CID	126970684

PubChem CID	126970684

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1. Hasan M, Yan N. (2016) Therapeutic potential of targeting TBK1 in autoimmune diseases and interferonopathies.. Pharmacol Res, 111 (3): (336-42). [PMID:27353409]
2. Vu HL, Aplin AE. (2014) Targeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma.. Mol Cancer Res, 12 (10): (1509-19). [PMID:24962318]

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