Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
A655705-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $440.90 |
Specifications & Purity | 10mM in DMSO |
---|---|
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pK i values of 7.93 and 9.06 for human CB1R and CB2R , respectively. AZD1940 shows a robust analgesia action In Vitro AZD1940 binds with high affinity to human, rat and mouse CB1 and CB2 receptors and displays full agonism at both receptors in all three species . MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo When given orally to rats, AZD1940 produces a robust analgesia in different models of inflammatory and neuropathic pain. For AZD1940, low brain uptake at analgesic doses has been demonstrated in both rats and primates . MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:hCB1-R 7.93 (pKi) hCB2-R 9.06 (pKi) |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Canonical SMILES | CCS(=O)(=O)NC1=CC2=C(C=C1)N(C(=N2)C(C)(C)C)CC3CCC(CC3)(F)F |
---|---|
Molecular Weight | 413.52 |
Enter Lot Number to search for COA: