| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A126496-5mg | 5mg | In stock | $103.90 | |
| A126496-25mg | 25mg | In stock | $468.90 | |
| A126496-100mg | 100mg | In stock | $848.90 |
| Synonyms | AZD3514|1240299-33-5|AZD-3514|1-(4-(2-(4-(1-(3-(Trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)piperazin-1-yl)ethanone|CS-1443|127DSS8X7J|CHEMBL2346976|AZD 3514 [WHO-DD]|1-[4-[2-[4-[1-[3-(trifluoromethyl)-7, |
|---|---|
| Specifications & Purity | ≥98% |
| Storage Temp | Store at -20°C |
| Shipped In | Dry ice |
| Action Type | MODULATOR |
| Mechanism of action | Androgen Receptor modulator |
| Product Description | AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression. |
| ALogP | 1.7 |
|---|
| IUPAC Name | 1-[4-[2-[4-[1-[3-(trifluoromethyl)-7,8-dihydro-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]phenoxy]ethyl]piperazin-1-yl]ethanone |
|---|---|
| INCHI | InChI=1S/C25H32F3N7O2/c1-18(36)33-14-12-32(13-15-33)16-17-37-21-4-2-19(3-5-21)20-8-10-34(11-9-20)23-7-6-22-29-30-24(25(26,27)28)35(22)31-23/h2-5,20H,6-17H2,1H3 |
| InChi Key | JMEYDSHPKCSIJC-UHFFFAOYSA-N |
| Canonical SMILES | CC(=O)N1CCN(CC1)CCOC2=CC=C(C=C2)C3CCN(CC3)C4=NN5C(=NN=C5C(F)(F)F)CC4 |
| Isomeric SMILES | CC(=O)N1CCN(CC1)CCOC2=CC=C(C=C2)C3CCN(CC3)C4=NN5C(=NN=C5C(F)(F)F)CC4 |
| PubChem CID | 46893585 |
| Molecular Weight | 519.56 |
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| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 I2221085 | Certificate of Analysis | Jul 19, 2024 | A126496 |
| I2221149 | Certificate of Analysis | Jul 19, 2024 | A126496 |
| I2221157 | Certificate of Analysis | Jul 19, 2024 | A126496 |
| Solubility | 25°C: DMSO |
|---|
| Pictogram(s) | GHS06 |
|---|---|
| Signal | Danger |
| Hazard Statements | H301:Toxic if swallowed |
| Precautionary Statements | P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately. |
