AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase ( MPO ) with an IC 50 of 140 nM and has similar potency in mouse and rat.
In Vitro
AZD5904 is a pselective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC 50 of 140 nM and has similar potency in mouse and rat. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase; >70-fold to a broad panel of other enzymes, ion channels, and receptors. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
