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AZD9056 hydrochloride , CAS No.345304-65-6

  • Moligand™
  • ≥98%
Item Number
A607893
Grouped product items
SKUSizeAvailabilityPrice Qty
A607893-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$36.90
A607893-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$88.90
A607893-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$149.90
A607893-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90
A607893-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$557.90
View related series
P2X Receptor

Basic Description

SynonymsAKOS030228502|n-(1-adamantylmethyl)-2-chloro-5-(3-(3-hydroxypropylamino)propyl)benzamide|HSQAARMBHJCUOK-UHFFFAOYSA-N|AC-36649|AZD-9056 free base|EX-A6120|F13K378W4L|BDBM50267791|UNII-F13K378W4L|2-Chloro-5-[3-[(3-hydroxypropyl)amino]propyl]-N-(tricyclo[3.3
Specifications & Purity98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

AZD9056 hydrochloride is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases.

Associated Targets

P2RX7 Tchem P2X purinoceptor 7 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-(1-adamantylmethyl)-2-chloro-5-[3-(3-hydroxypropylamino)propyl]benzamide;hydrochloride
INCHI InChI=1S/C24H35ClN2O2.ClH/c25-22-5-4-17(3-1-6-26-7-2-8-28)12-21(22)23(29)27-16-24-13-18-9-19(14-24)11-20(10-18)15-24;/h4-5,12,18-20,26,28H,1-3,6-11,13-16H2,(H,27,29);1H
InChi Key LZBBHFRRZLDHLE-UHFFFAOYSA-N
Canonical SMILES C1C2CC3CC1CC(C2)(C3)CNC(=O)C4=C(C=CC(=C4)CCCNCCCO)Cl.Cl
Isomeric SMILES C1C2CC3CC1CC(C2)(C3)CNC(=O)C4=C(C=CC(=C4)CCCNCCCO)Cl.Cl
Alternate CAS 345303-91-5
PubChem CID 10161380
Molecular Weight 455.46

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2417175Certificate of AnalysisApr 09, 2024 A607893
G2417176Certificate of AnalysisApr 09, 2024 A607893
G2417177Certificate of AnalysisApr 09, 2024 A607893
G2417181Certificate of AnalysisApr 09, 2024 A607893
G2417182Certificate of AnalysisApr 09, 2024 A607893
G2417185Certificate of AnalysisApr 09, 2024 A607893
G2417192Certificate of AnalysisApr 09, 2024 A607893
G2417193Certificate of AnalysisApr 09, 2024 A607893
G2417197Certificate of AnalysisApr 09, 2024 A607893
G2417206Certificate of AnalysisApr 09, 2024 A607893

Chemical and Physical Properties

SensitivityMoisture sensitive

Related Documents

References

1. McInnes IB, Cruwys S, Bowers K, Braddock M.  (2014)  Targeting the P2X7 receptor in rheumatoid arthritis: biological rationale for P2X7 antagonism..  Clin Exp Rheumatol,  32  (6): (878-82).  [PMID:25288220]

Solution Calculators