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Azelastine HCl - ≥98%(HPLC), high purity , Histamine H1 receptor antagonist, CAS No.79307-93-0, Histamine H1 receptor antagonist
Basic Description Synonyms AZELASTINE HYDROCHLORIDE|79307-93-0|AZELASTINE HCl|Astelin|Optivar|Allergodil|Azeptin|Rhinolast|Astepro|Azelastine (hydrochloride)|W-2979M|Zalastine|37932-96-0|E-0659|4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one hydrochloride|A-5610|Opti Specifications & Purity ≥98%(HPLC) Biochemical and Physiological Mechanisms Azelastine HCl is an Histamine H1 Receptor (H1-receptor) antagonist, with antiallergic effects related to histamine antagonism, and further antiallergic and antiinflammatory effects unrelated to H1-receptor binding. Azelastine is shown to block secretion Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Action Type ANTAGONIST Mechanism of action Histamine H1 receptor antagonist Note 250mg、100mg卖完停产，不再备货 Product Description Azelastine HCl is a potent, second-generation, selective, histamine antagonist
Names and Identifiers Pubchem Sid 488183381 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488183381 IUPAC Name 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one;hydrochloride INCHI InChI=1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H InChi Key YEJAJYAHJQIWNU-UHFFFAOYSA-N Canonical SMILES CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl Isomeric SMILES CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl.Cl RTECS TH9203900 PubChem CID 54360 Molecular Weight 418.36 Reaxy-Rn 4834474
Chemical and Physical Properties Solubility Soluble in water (25 mg/mL), DMSO (>10 mg/mL), and ethanol. Sensitivity Moisture & heat sensitive Melt Point(°C) 226 °C
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Warning Hazard Statements H302: Harmful if swallowed
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P301+P317: IF SWALLOWED: Get medical help.
P318: if exposed or concerned, get medical advice.
RTECS TH9203900 Reaxy-Rn 4834474 Merck Index 906
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