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Home Bioactive Small Molecules Azelnidipine - ≥99%, high purity , Voltage-gated L-type calcium channel blocker, CAS No.123524-52-7, Voltage-gated L-type calcium channel blocker
Azelnidipine - ≥99%, high purity , Voltage-gated L-type calcium channel blocker, CAS No.123524-52-7, Voltage-gated L-type calcium channel blocker
Basic Description Synonyms Azelnidipine|123524-52-7|3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate|Calblock|Azelnidipine [INN]|CS-905|CS 905|PV23P19YUG|DTXSID3020120|3,5-PYRIDINEDICARBOXYLIC ACID, 2-AMINO-1,4-DIHYD Specifications & Purity ≥99% Biochemical and Physiological Mechanisms Azelnidipine is a novel dihydropyridine derivative, an L-type calcium channel protein inhibitor and an antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its si Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Action Type BLOCKER Mechanism of action Voltage-gated L-type calcium channel blocker Note 5g、1g卖完停产，不再备货 Product Description Azelnidipine is a dihydropyridine calcium channel blocker
Names and Identifiers IUPAC Name 3-O-(1-benzhydrylazetidin-3-yl) 5-O-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate INCHI InChI=1S/C33H34N4O6/c1-20(2)42-32(38)27-21(3)35-31(34)29(28(27)24-15-10-16-25(17-24)37(40)41)33(39)43-26-18-36(19-26)30(22-11-6-4-7-12-22)23-13-8-5-9-14-23/h4-17,20,26,28,30,35H,18-19,34H2,1-3H3 InChi Key ZKFQEACEUNWPMT-UHFFFAOYSA-N Canonical SMILES CC1=C(C(C(=C(N1)N)C(=O)OC2CN(C2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC(C)C Isomeric SMILES CC1=C(C(C(=C(N1)N)C(=O)OC2CN(C2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC(C)C WGK Germany 3 RTECS US7968332 PubChem CID 65948 Molecular Weight 582.65
Chemical and Physical Properties Solubility Soluble in DMSO: >10 mg/mL Sensitivity Air sensitive
Safety and Hazards(GHS) Pictogram(s) GHS05 , GHS07 Signal Danger Hazard Statements H302: Harmful if swallowed
H318: Causes serious eye damage
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P301+P317: IF SWALLOWED: Get medical help.
P305+P354+P338: IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.
P317: Get emergency medical help.
WGK Germany 3 RTECS US7968332 Merck Index 907
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