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Azoramide - 98%, high purity , CAS No.932986-18-0
Unfolded protein response (UPR) modulator
Basic Description Synonyms CCG-267569 | BRD-K67416388-001-01-3 | N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide | SCHEMBL21523880 | Azoramide, >=98% (HPLC) | NCGC00484058-03 | s8304 | BCP23896 | NCGC00484058-01 | CS-4954 | N-{2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl Specifications & Purity ≥98% Biochemical and Physiological Mechanisms Modulator of unfolded protein response (UPR). Protects cells from ER stress by improving ER protein folding and activating ER chaperone capacity. Also improves ER calcium retention. Improves liver ER function, glucose homeostasis and glucose-stimulated in Shipped In Normal
Names and Identifiers IUPAC Name N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide INCHI InChI=1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19) InChi Key VYBFWKKCWTXCQX-UHFFFAOYSA-N Canonical SMILES CCCC(=O)NCCC1=CSC(=N1)C2=CC=C(C=C2)Cl Isomeric SMILES CCCC(=O)NCCC1=CSC(=N1)C2=CC=C(C=C2)Cl PubChem CID 7518316 Molecular Weight 308.83
Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 30.88, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 30.88, Max Conc. mM: 100 Molecular Weight 308.800 g/mol XLogP3 3.700 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 6 Exact Mass 308.075 Da Monoisotopic Mass 308.075 Da Topological Polar Surface Area 70.200 Ų Heavy Atom Count 20 Formal Charge 0 Complexity 308.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Citations of This Product1 ) 1. Fengying Dai, Kepeng Lv, Bo Zhang, Junqiang Zhao, Shaoteng Wang, Ke Lan, Yiping Zhao, Xiaolei Zhang, Bohong Kan. (2023) Overcoming the structure deficiency of nanodrug coated with tannic acid shell through phenolic hydroxyl protection strategy for Alzheimer's disease combination treatment. Biomaterials Advances, 154 (21): (213651). [PMID:37827021 ] [10.1016/j.bioadv.2023.213651 ]
References 1. Fengying Dai, Kepeng Lv, Bo Zhang, Junqiang Zhao, Shaoteng Wang, Ke Lan, Yiping Zhao, Xiaolei Zhang, Bohong Kan. (2023) Overcoming the structure deficiency of nanodrug coated with tannic acid shell through phenolic hydroxyl protection strategy for Alzheimer's disease combination treatment. Biomaterials Advances, 154 (21): (213651). [PMID:37827021 ] [10.1016/j.bioadv.2023.213651 ]
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