β-Glycerophosphate disodium salt hydrate

Item Number
G755749
Grouped product items
SKUSizeAvailabilityPrice Qty
G755749-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$68.90
G755749-50g
50g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$181.90
G755749-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$304.90
G755749-500g
500g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,080.90

Basic Description

Specifications & PurityBioUltra, for cell culture, for plant cell culture, ≥99%(T)
Storage TempRoom temperature
Shipped InNormal
GradeBioUltra, for cell culture, for plant cell culture
Product Description

Glycerophosphoric acid disodium salt hydrate, also known as BGP, is a versatile compound with applications across various research domains, including cell biology, biochemical research, and metabolomics. Recognized as an endogenous metabolite and a serine-threonine phosphatase inhibitor, BGP is extensively utilized in chitosan hydrogel formulations for drug delivery research. It serves as a phosphate source for cell growth and recombinant protein production, offering advantages in media formulations by reducing precipitation at higher pH levels. Additionally, BGP finds applications in micro-arc oxidation electrolyte solutions, contributing to the creation of photocatalytic coatings.
In cell biology, β-Glycerophosphate disodium salt plays a pivotal role as a phosphate group donor in matrix mineralization studies and accelerates calcification in vascular smooth muscle cells. It also promotes bone matrix mineralization when delivered to osteoblasts, providing a crucial source of phosphate ions. In the realm of biochemical research, BGP functions as a classical serine-threonine phosphatase inhibitor in kinase reaction buffers, offering broad-spectrum inhibition. Its role as an organic phosphate donor is particularly valuable in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. Moreover, BGP is utilized to buffer M17 media for Lactococcus culture in recombinant protein expression. The comprehensive utility of BGP spans multiple areas of research, making it an essential component in studies encompassing cell biology, biochemical research, and metabolomics.
Application:
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression.
Initiates differentiation of bone-marrow-derived stem cells embedded in a natural collagen/chitosan gel designed for tissue engineering.

Names and Identifiers

IUPAC Name disodium;1,3-dihydroxypropan-2-yl phosphate;hydrate
INCHI InChI=1S/C3H9O6P.2Na.H2O/c4-1-3(2-5)9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2
InChi Key ROPZSVKNEIIIDE-UHFFFAOYSA-L
Canonical SMILES C(C(CO)OP(=O)([O-])[O-])O.O.[Na+].[Na+]
Isomeric SMILES C(C(CO)OP(=O)([O-])[O-])O.O.[Na+].[Na+]
PubChem CID 16219387
Molecular Weight 216.04 (anhydrous basis)

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubilitywater: soluble
Melt Point(°C)102~104 ℃

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H335:May cause respiratory irritation

Related Documents

Solution Calculators