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β-Nicotinamide adenine dinucleotide（NAD） - >98.0%（HPLC), high purity , CAS No.53-84-9

Moligand™
≥98%(HPLC)

CAS#: 53-84-9
Formula: C₂₁H₂₇N₇O₁₄P₂ · xH₂O
Molecular Weight: 663.43 (anhydrous basis)
Beilstein Registry Number: 3584133
EC Number: 200-184-4
MDL number: MFCD00036253
PubChem CID: 5892

Item Number

N111610

Grouped product items
SKU	Size	Availability	Price
N111610-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$11.90
N111610-1g	1g	In stock	$13.90
N111610-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$32.90
N111610-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$95.90

Coenzyme and enzyme substrate. P2Y 11 agonist.

View related series

P2Y11 receptor Agonist TRPM2 Activator

Basic Description

Synonyms	nadide\|NAD+\|53-84-9\|coenzyme I\|beta-NAD\|beta-nicotinamide adenine dinucleotide\|Codehydrase I\|Codehydrogenase I\|nicotinamide adenine dinucleotide\|beta-NAD+\|Cozymase I\|diphosphopyridine nucleotide\|beta-Diphosphopyridine nucleotide\|COZYMASE\|Nicotinamide dinu
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	β-Nicotinamide adenine dinucleotide hydrate has been used as a component of fibroblast cell culture media.[1] It has also been used to study the viability of the cartilage constructs. β-Nicotinamide adenine dinucleotide hydrate was used as a test compoun
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	NAD+, Free Acid is a major electron acceptor molecule in biological oxidation reactions. A major electron acceptor

Associated Targets

GLUD1 Tbio Glutamate dehydrogenase 1, mitochondrial 0 Activities

Discover Target: GLUD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSD17B1 Tchem Estradiol 17-beta-dehydrogenase 1 0 Activities

Discover Target: HSD17B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPM2 Tchem Transient receptor potential cation channel subfamily M member 2 0 Activities

Discover Target: TRPM2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 0 Activities

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Discover Target: SLCO1B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Discover Target: SLCO1B3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SIRT1 Tchem NAD-dependent protein deacetylase sirtuin-1 0 Activities

Discover Target: SIRT1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LDHB Tchem L-lactate dehydrogenase B chain 0 Activities

Discover Target: LDHB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MDH1 Tchem Malate dehydrogenase, cytoplasmic 0 Activities

Discover Target: MDH1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADH1A Tclin Alcohol dehydrogenase 1A 0 Activities

Discover Target: ADH1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHAT Tchem Choline O-acetyltransferase 0 Activities

Discover Target: CHAT

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IMPDH2 Tclin Inosine-5'-monophosphate dehydrogenase 2 0 Activities

Discover Target: IMPDH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY11 Tchem P2Y purinoceptor 11 0 Activities

Discover Target: P2RY11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

LDHA Tchem L-lactate dehydrogenase A chain 0 Activities

Discover Target: LDHA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
INCHI	InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChi Key	BAWFJGJZGIEFAR-NNYOXOHSSA-N
Canonical SMILES	C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
Isomeric SMILES	C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
WGK Germany	3
RTECS	UU3450000
PubChem CID	5892
Molecular Weight	663.43 (anhydrous basis)
Beilstein	3584133
Reaxy-Rn	3584133

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

25 results found

Lot Number	Certificate Type	Date	Item
H2423381	Certificate of Analysis	Jul 27, 2024	N111610
H2423374	Certificate of Analysis	Jul 27, 2024	N111610
H2423373	Certificate of Analysis	Jul 27, 2024	N111610
C2426274	Certificate of Analysis	Mar 08, 2024	N111610
C2426275	Certificate of Analysis	Mar 08, 2024	N111610
C2426276	Certificate of Analysis	Mar 08, 2024	N111610
C2426277	Certificate of Analysis	Mar 08, 2024	N111610
J2308656	Certificate of Analysis	Sep 25, 2023	N111610
J2308611	Certificate of Analysis	Sep 25, 2023	N111610
G2326326	Certificate of Analysis	Jun 19, 2023	N111610
G2326303	Certificate of Analysis	Jun 19, 2023	N111610
A2312195	Certificate of Analysis	Dec 21, 2022	N111610
A2312201	Certificate of Analysis	Dec 21, 2022	N111610
A2312200	Certificate of Analysis	Dec 21, 2022	N111610
A2312180	Certificate of Analysis	Dec 21, 2022	N111610
K2215083	Certificate of Analysis	Nov 22, 2022	N111610
K2204569	Certificate of Analysis	Aug 26, 2022	N111610
K2204628	Certificate of Analysis	Aug 26, 2022	N111610
K2204629	Certificate of Analysis	Aug 26, 2022	N111610
K2204659	Certificate of Analysis	Aug 26, 2022	N111610
K2204661	Certificate of Analysis	Aug 26, 2022	N111610
F2222480	Certificate of Analysis	Jun 30, 2022	N111610
G2223243	Certificate of Analysis	Jun 16, 2022	N111610
G2223230	Certificate of Analysis	Jun 16, 2022	N111610
G2223224	Certificate of Analysis	Jun 16, 2022	N111610

Chemical and Physical Properties

Solubility	Soluble in water (200 mg/ml).
Sensitivity	Moisture & heat sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	UU3450000
Reaxy-Rn	3584133
Merck Index	6344

Alternative Products

References

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