N-Bromosuccinimide - Analytical Reagent,99.00%, high purity , CAS No.128-08-5

  • AR
  • ≥99%
Item Number
B105057
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B105057-25g
25g
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$14.90
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100g
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$38.90
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250g
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$64.90
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500g
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$103.90

Basic Description

SynonymsCS-W008781 | NSC 16 | SCHEMBL58 | Q286939 | Succinbromide | Succinibromimide | FT-0645778 | J-005565 | MFCD00005510 | N-bromosuccinimid | N-Bromosuccinimide (NBS) | CCRIS 2899 | N-brornosuccinimide | 2, 1-bromo- | BP-30011 | N-Bromopyrrolidine-2,5-dione |
Specifications & PurityAR, ≥99%
Storage TempStore at 2-8°C,Protected from light,Argon charged
Shipped InWet ice
GradeAR
Product Description

Common brominating agent. Oxidizes silyl ethers to aldehydes in the presence of AIBN. Versatile brominating agent. For the oxidation of tryptophan though tyrosine, histidine and methionine residues may be oxidized to a lesser extent. Also used for the modification of ribosomal sulfhydryl groups.


Product Application:

N-Bromosuccinimide can be used as a reagent:
In the Wohl-Ziegler reaction (bromination at allylic positions via a radical pathway).
To synthesize benzils and aliphatic 1,2-diketones from hydrobenzoins and 1,2-diols in the presence of CCl4 as a solvent.
To prepare tricyclic azepino[4,5-b]indoles from indole-β-enaminoesters or β-enaminones via Pictet–Spengler cyclization.
To synthesize acylsilanes via oxidative hydrolysis of 2-silyl-1,3-dithianes.

Names and Identifiers

IUPAC Name 1-bromopyrrolidine-2,5-dione
INCHI InChI=1S/C4H4BrNO2/c5-6-3(7)1-2-4(6)8/h1-2H2
InChi Key PCLIMKBDDGJMGD-UHFFFAOYSA-N
Canonical SMILES C1CC(=O)N(C1=O)Br
Isomeric SMILES C1CC(=O)N(C1=O)Br
WGK Germany 3
PubChem CID 67184
UN Number 3261
Packing Group III
Molecular Weight 177.98
Beilstein 113916
Reaxy-Rn 113916

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in acetone, tetrahydrofuran, dimethyl formamide, dimethyl sulfoxide and acetonitrile. Slightly soluble in water and acetic acid. Insoluble in ether, hexane and carbon tetrachloride.
SensitivityLight sensitive.Heat and Moisture Sensitive
Boil Point(°C)339 °C
Melt Point(°C)175-180°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS09,   GHS05,   GHS07,   GHS03
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H314:Causes severe skin burns and eye damage

H302:Harmful if swallowed

H400:Very toxic to aquatic life

H272:May intensify fire; oxidizer

H290:May be corrosive to metals

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P220:Keep away from clothing and other combustible materials.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P363:Wash contaminated clothing before reuse.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P391:Collect spillage.

P330:Rinse mouth.

P234:Keep only in original container.

P390:Absorb spillage to prevent material damage.

P406:Store in corrosive resistant/... container with a resistant inner liner.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes.

P316:Get emergency medical help immediately.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 113916
Class 8
Merck Index 1438

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Solution Calculators