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Bathocuproinedisulfonic acid disodium salt hydrate , CAS No.1257642-74-2

Item Number
B486593
Grouped product items
SKUSizeAvailabilityPrice Qty
B486593-250mg
250mg
In stock
$179.90
B486593-1g
1g
In stock
$453.90
View related series
Chelating agent Pyridines

Basic Description

Synonyms1257642-74-2|Bathocuproinedisulfonic acid disodium salt hydrate|Sodium 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate hydrate|disodium;2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate;hydrate|Disodium bathocuproine disulfonate|
Product Description

Bathocuproine disulfonic acid (BCDS) is a stable Cu+chelator and BCDS-Cu+inhibits the HIV-1 wild type protease as well as a mutant HIV-1 protease lacking cysteine. It is an extracellular copper chelator.Bathocuproinedisulfonic acid disodium salt hydrate was used as chelator in electron spin resonance spin trapping technique to study free radical generation in rats with acute sodium formate poisoning. It was used as reagent for determination of Cu and Cu-protein complexes.

Names and Identifiers

Pubchem Sid488202189
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488202189
IUPAC Name disodium;2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate;hydrate
INCHI InChI=1S/C26H20N2O6S2.2Na.H2O/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;;1H2/q;2*+1;/p-2
InChi Key ZAGWMJUGRCMNGX-UHFFFAOYSA-L
Canonical SMILES CC1=C(C(=C2C=CC3=C(C(=C(N=C3C2=N1)C)S(=O)(=O)[O-])C4=CC=CC=C4)C5=CC=CC=C5)S(=O)(=O)[O-].O.[Na+].[Na+]
Isomeric SMILES CC1=C(C(=C2C=CC3=C(C(=C(N=C3C2=N1)C)S(=O)(=O)[O-])C4=CC=CC=C4)C5=CC=CC=C5)S(=O)(=O)[O-].O.[Na+].[Na+]
WGK Germany 3
PubChem CID 71306850
Molecular Weight 564.54 (anhydrous basis)

Certificates

Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
C2414332Certificate of AnalysisFeb 24, 2024 B486593
C2414333Certificate of AnalysisFeb 24, 2024 B486593
C2414334Certificate of AnalysisFeb 24, 2024 B486593
C2414335Certificate of AnalysisFeb 24, 2024 B486593
F2309240Certificate of AnalysisApr 10, 2023 B486593
F2309241Certificate of AnalysisApr 10, 2023 B486593
F2309242Certificate of AnalysisApr 10, 2023 B486593
F2309244Certificate of AnalysisApr 10, 2023 B486593

Safety and Hazards(GHS)

Signal Warning
Hazard Statements

H413:May cause long lasting harmful effects to aquatic life

H302:Harmful if swallowed

Precautionary Statements

P273:Avoid release to the environment.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P301+P312+P330:IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. Rinse mouth.

WGK Germany 3
RIDADR NONHforallmodesoftransport

Related Documents

References

1. D A Davis,A A Branca,A J Pallenberg,T M Marschner,L M Patt,L G Chatlynne,R W Humphrey,R Yarchoan,R L Levine.  (1995-09-10)  Inhibition of the human immunodeficiency virus-1 protease and human immunodeficiency virus-1 replication by bathocuproine disulfonic acid Cu1+..  Archives of biochemistry and biophysics,  322  ((1)): (127-134).  [PMID:7574666]
2. M Matsushita,T Irino,T Komoda,Y Sakagishi.  (1993-07-16)  Determination of proteins by a reverse biuret method combined with the copper-bathocuproine chelate reaction..  Clinica chimica acta; international journal of clinical chemistry,  216  ((1-2)): (103-111).  [PMID:8222260]
3. Dieter Egli,Anand Selvaraj,Hasmik Yepiskoposyan,Bo Zhang,Ernst Hafen,Oleg Georgiev,Walter Schaffner.  (2002-12-31)  Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis..  The EMBO journal,  22  ((1)): (100-108).  [PMID:12505988]
4. Eric Bakker.  (2010-08-10)  Generalized Selectivity Description for Polymeric Ion-Selective Electrodes Based on the Phase Boundary Potential Model..  Journal of electroanalytical chemistry (Lausanne, Switzerland),  639  ((1-2)): (1-7).  [PMID:20694153]
5. Qiong Hu,Baojing Zhou,Feng Li,Jinming Kong,Xueji Zhang.  (2016-09-13)  Turn-On Colorimetric Platform for Dual Activity Detection of Acid and Alkaline Phosphatase in Human Whole Blood..  Chemistry, an Asian journal,  11  ((21)): (3040-3045).  [PMID:27615725]
6. Monirul Islam,Massimo E Maffei,Gianpiero Vigani.  (2020-05-07)  The Geomagnetic Field Is a Contributing Factor for an Efficient Iron Uptake in Arabidopsis thaliana..  Frontiers in plant science,  11  (325-325).  [PMID:32373135]

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