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BAY 8002 - ≥98%(HPLC), high purity , CAS No.724440-27-1, Inhibitor of Monocarboxylate transporter 1;Inhibitor of Monocarboxylate transporter 2

Moligand™
≥98%(HPLC)

CAS#: 724440-27-1
Formula: C₂₀H₁₄ClNO₅S
Molecular Weight: 415.85
PubChem CID: 992293

Item Number

B288827

Grouped product items
SKU	Size	Availability	Price
B288827-5mg	5mg	In stock	$93.90
B288827-10mg	10mg	In stock	$137.90
B288827-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$424.90
B288827-100mg	100mg	In stock	$692.90

Potent dual MCT1/2 inhibitor

View related series

Monocarboxylate transporter 1 Inhibitor Monocarboxylate transporter 2 Inhibitor

Basic Description

Synonyms	2-[[2-Chloro-5-(phenylsulfonyl)benzoyl]amino]benzoic acid
Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of Monocarboxylate transporter 1;Inhibitor of Monocarboxylate transporter 2

Associated Targets

SLC16A7 Tchem Monocarboxylate transporter 2 0 Activities

Discover Target: SLC16A7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC16A1 Tchem Monocarboxylate transporter 1 0 Activities

Discover Target: SLC16A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-[[5-(benzenesulfonyl)-2-chlorobenzoyl]amino]benzoic acid
INCHI	InChI=1S/C20H14ClNO5S/c21-17-11-10-14(28(26,27)13-6-2-1-3-7-13)12-16(17)19(23)22-18-9-5-4-8-15(18)20(24)25/h1-12H,(H,22,23)(H,24,25)
InChi Key	CLAUJSRBKSRTGQ-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)S(=O)(=O)C2=CC(=C(C=C2)Cl)C(=O)NC3=CC=CC=C3C(=O)O
Isomeric SMILES	C1=CC=C(C=C1)S(=O)(=O)C2=CC(=C(C=C2)Cl)C(=O)NC3=CC=CC=C3C(=O)O
PubChem CID	992293
MeSH Entry Terms	2-(((2-chloro-5-(phenylsulfonyl)phenyl)-carbonyl)amino)benzoic acid;BAY-8002
Molecular Weight	415.85

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
J2113379	Certificate of Analysis	Jul 18, 2024	B288827
J2113380	Certificate of Analysis	Jul 18, 2024	B288827
J2113381	Certificate of Analysis	Jul 18, 2024	B288827
J2113382	Certificate of Analysis	Jul 18, 2024	B288827

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

References

1. Quanz M, Bender E, Kopitz C, Grünewald S, Schlicker A, Schwede W, Eheim A, Toschi L, Neuhaus R, Richter C et al.. (2018) Preclinical Efficacy of the Novel Monocarboxylate Transporter 1 Inhibitor BAY-8002 and Associated Markers of Resistance.. Mol Cancer Ther, 17 (11): (2285-2296). [PMID:30115664]

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