BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor ( IC 50 =81 nM). BAY-8400 can be used for the research of cancer
In Vivo
BAY-8400 (150 mg/kg; p.o.) increases the antitumor efficacy. BAY-8400 shows useful aqueous\nsolubility and oral bioavailability across species . MCE has not independently confirmed the accuracy of these methods. They are for reference only.