BCN-PEG3-VC-PFP Ester - 96%, high purity , CAS No.2353409-45-5

Item Number

B597155

Grouped product items
SKU	Size	Availability	Price
B597155-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,441.90
B597155-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,521.90
B597155-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,801.90
B597155-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$8,401.90

Val-Cit

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Basic Description

Specifications & Purity	96%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	BCN-PEG3-VC-PFP Ester is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The BCN group can react with azide-tagged biomolecules. The PFP ester is a better leaving group compared to a hydroxyl group and can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

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Basic Description