| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| B654896-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $462.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Storage Temp | Desiccated,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D ( IC 50 =96 nM) and C1s ( IC 50 =1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin. In Vitro BCX 1470 methanesulfonate is serine protease inhibitor. BCX 1470 methanesulfonate blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro, also blocked development of RPA-induced edema in the rat. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 96 nM (Factor D),1.6 nM (C1s),326 nM (Trypsin) |
| Canonical SMILES | N=C(C1=CC2=CC=C(OC(C3=CC=CS3)=O)C=C2S1)N.O=S(O)(C)=O |
|---|---|
| Molecular Weight | 398.48 |
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