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Benzamidine hydrochloride - 98%, high purity , CAS No.1670-14-0
Basic Description Synonyms Benzamidine hydrochloride|1670-14-0|Benzimidamide hydrochloride|BENZAMIDINE HCL|Benzenecarboximidamide, monohydrochloride|Benzenecarboximidamide hydrochloride|Amidinobenzene hydrochloride|Benzamidinium chloride|Benzamidine, monohydrochloride|Amidinobenzen Specifications & Purity ≥98% Storage Temp Store at 2-8°C,Argon charged Shipped In Wet ice Product Description Benzamidine and its derivatives serve as inhibitors of serine protease enzymes, namely tryptase, thrombin, and KLK11 (tripsin-like enzymes). The strong affinity of benzamidine for these enzymes has been exploited to crystallize and study spectra of thrombin complexes. Benzamidine inhibits the autoactivation of human blood coagulation factor VII, useful as a tool for studying the interactions between this and other relevant growth factors. A derivative of this compound has shown activity against the growth of colon cancer cells.
Names and Identifiers IUPAC Name benzenecarboximidamide;hydrochloride INCHI InChI=1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H InChi Key LZCZIHQBSCVGRD-UHFFFAOYSA-N Canonical SMILES C1=CC=C(C=C1)C(=N)N.Cl Isomeric SMILES C1=CC=C(C=C1)C(=N)N.Cl WGK Germany 3 RTECS CV6260000 PubChem CID 80289 Molecular Weight 156.61 Beilstein 3594959 Reaxy-Rn 3594959
Chemical and Physical Properties Solubility Soluble in water. Sensitivity Moisture sensitive Melt Point(°C) 167-171°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3 RTECS CV6260000 Reaxy-Rn 3594959
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