Determine the necessary mass, volume, or concentration for preparing a solution.
Basic Description
| Synonyms | BENZOYL CHLORIDE|98-88-4|Benzoic acid, chloride|Benzenecarbonyl chloride|Benzoylchloride|alpha-Chlorobenzaldehyde|benzoic acid chloride|Benzaldehyde, alpha-chloro-|CCRIS 802|HSDB 383|EINECS 202-710-8|UNII-VTY8706W36|BRN 0471389|DTXSID9026631|CHEBI:82275|B |
|---|---|
| Specifications & Purity | ACS, ≥99%(T) |
| Storage Temp | Argon charged |
| Shipped In | Normal |
| Grade | ACS |
| Product Description | Application Benzoyl chloride may be used in the synthesis of the following organic building blocks: N,N-diethylbenzamide via condensation with diethylamine N-2-bromophenylbenzamide by reacting with 2-bromoaniline via N-benzoylation propargyl benzoate via O-benzoylation of propargyl alcohol |
Names and Identifiers
| IUPAC Name | benzoyl chloride |
|---|---|
| INCHI | InChI=1S/C7H5ClO/c8-7(9)6-4-2-1-3-5-6/h1-5H |
| InChi Key | PASDCCFISLVPSO-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC=C(C=C1)C(=O)Cl |
| Isomeric SMILES | C1=CC=C(C=C1)C(=O)Cl |
| WGK Germany | 1 |
| RTECS | DM6600000 |
| PubChem CID | 7412 |
| UN Number | 1736 |
| Packing Group | II |
| Molecular Weight | 140.57 |
| Beilstein | 471389 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 I2216069 | Certificate of Analysis | Jun 12, 2024 | B104566 |
| G2129027 | Certificate of Analysis | May 11, 2023 | B104566 |
| A2312070 | Certificate of Analysis | Dec 13, 2022 | B104566 |
Chemical and Physical Properties
| Solubility | Miscible with water, ether, benzene, carbon disulfide and carbon tetra chloride. |
|---|---|
| Sensitivity | Moisture & Air sensitive. |
| Refractive Index | 1.55369 |
| Flash Point(°F) | 161.6 °F |
| Flash Point(°C) | 88℃ |
| Boil Point(°C) | 197.2°C |
| Melt Point(°C) | -1°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS06, GHS09, GHS05 |
|---|---|
| Signal | Danger |
| Hazard Statements | H314:Causes severe skin burns and eye damage H302:Harmful if swallowed H317:May cause an allergic skin reaction H312:Harmful in contact with skin H332:Harmful if inhaled |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately. |
| WGK Germany | 1 |
| RTECS | DM6600000 |
| Class | 8 |
| Merck Index | 1112 |
Related Documents
Alternative Products
-
Benzoyl chlorideStarting at $14.90
- p-Toluoyl chloride
Starting at $15.90
- 4-Methoxybenzoyl chloride
Starting at $37.90
- Benzoyl chloride
Starting at $18.90
References
| 1. . (1999-09-07) alpha-Chlorinated toluenes and benzoyl chloride.. IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 2 (453-477). [PMID:10476457] |
| 2. Giuliana Biagi,Irene Giorgi,Oreste Livi,Antonio Nardi,Vincenzo Calderone,Alma Martelli,Enrica Martinotti,Oreste LeRoy Salerni. (2004-06-09) Synthesis and biological activity of novel substituted benzanilides as potassium channel activators. V.. European journal of medicinal chemistry, 39 ((6)): (491-498). [PMID:15183907] |
| 3. Sarah D Lever,Maria Papadaki. (2004-11-03) Study of condition-dependent decomposition reactions; Part I. The thermal behaviour and decomposition of 2-nitrobenzoyl chloride.. Journal of hazardous materials, 115 ((1-3)): (91-100). [PMID:15518968] |
| 4. T William Bentley,David N Ebdon,Eun-Ju Kim,In Sun Koo. (2005-02-26) Solvent polarity and organic reactivity in mixed solvents: evidence using a reactive molecular probe to assess the role of preferential solvation in aqueous alcohols.. The Journal of organic chemistry, 70 ((5)): (1647-1653). [PMID:15730284] |
| 5. Sarah D Lever,Maria Papadaki. (2005-10-21) Effects of heating rate, temperature and iron catalysis on the thermal behaviour and decomposition of 2-nitrobenzoyl chloride.. Journal of hazardous materials, 130 ((1-2)): (76-87). [PMID:16236442] |
| 6. Weike Su,Can Jin. (2007-02-24) First catalytic and green synthesis of aryl-(Z)-vinyl chlorides and its plausible addition-elimination mechanism.. Organic letters, 9 ((6)): (993-996). [PMID:17316010] |
| 7. Kenneth B Wiberg,Yi-gui Wang,Scott J Miller,Angela L A Puchlopek,William F Bailey,Justin D Fair. (2009-04-18) Disparate behavior of carbonyl and thiocarbonyl compounds: acyl chlorides vs thiocarbonyl chlorides and isocyanates vs isothiocyanates.. The Journal of organic chemistry, 74 ((10)): (3659-3664). [PMID:19371054] |
| 8. C Cabaleiro-Lago,L García-Río,P Hervés,J Pérez-Juste. (2009-04-22) Fully uncomplexed cyclodextrin in mixed systems of vesicle-cyclodextrin: solvolysis of benzoyl chlorides.. The journal of physical chemistry. B, 113 ((19)): (6749-6755). [PMID:19378985] |
| 9. P Campos-Rey,C Cabaleiro-Lago,P Hervés. (2010-10-20) Solvolysis of substituted benzoyl chlorides in nonionic and mixed micellar solutions.. The journal of physical chemistry. B, 114 ((44)): (14004-14011). [PMID:20954753] |
| 10. Ran Liu,Ying Jia,Weiming Cheng,Junhong Ling,Lili Liu,Kaishun Bi,Qing Li. (2010-12-15) Determination of polyamines in human urine by precolumn derivatization with benzoyl chloride and high-performance liquid chromatography coupled with Q-time-of-flight mass spectrometry.. Talanta, 83 ((3)): (751-756). [PMID:21147316] |
| 11. Luca Zoia,Alistair W T King,Dimitris S Argyropoulos. (2011-01-18) Molecular weight distributions and linkages in lignocellulosic materials derivatized from ionic liquid media.. Journal of agricultural and food chemistry, 59 ((3)): (829-838). [PMID:21235206] |
| 12. Trung Quan Luong,Pramod Kumar Verma,Rajib Kumar Mitra,Martina Havenith. (2011-11-03) Onset of hydrogen bonded collective network of water in 1,4-dioxane.. The journal of physical chemistry. A, 115 ((50)): (14462-14469). [PMID:22044284] |
| 13. Abbas Ali Esmaeili,Mahdieh Zangouei,Rahele Hosseinabadi,Ali Reza Fakhari. (2011-12-17) Three-component reactions of isocyanides, dialkyl acetylenedicarboxylates, and trans-cinnamoyl chlorides for the synthesis of highly functionalized 2-vinyl furans.. Molecular diversity, 16 ((1)): (145-150). [PMID:22173695] |
| 14. Ran Liu,Kaishun Bi,Ying Jia,Qian Wang,Ran Yin,Qing Li. (2012-09-29) Determination of polyamines in human plasma by high-performance liquid chromatography coupled with Q-TOF mass spectrometry.. Journal of mass spectrometry : JMS, 47 ((10)): (1341-1346). [PMID:23019166] |
| 15. Songbai Liu,Huina Ruan. (2012-12-25) A highly sensitive quantification of phytosterols through an inexpensive derivatization.. Chemistry and physics of lipids, 166 (18-25). [PMID:23261797] |
| 16. Surajit Rakshit,Ranajay Saha,Amrita Chakraborty,Samir Kumar Pal. (2013-01-15) Effect of hydrophobic interaction on structure, dynamics, and reactivity of water.. Langmuir : the ACS journal of surfaces and colloids, 29 ((6)): (1808-1817). [PMID:23311644] |
| 17. Ajuan Yu,Dongpo Peng,Kai Hu,Aijuan Cao,Junbiao Chang,Yangjie Wu,Shusheng Zhang. (2013-02-19) A new 4-ferrocenylbenzoyl chloride-bonded stationary phase for high performance liquid chromatography.. Journal of chromatography. A, 1283 (75-81). [PMID:23415442] |
| 18. Ying Dong,Yanhua Ma,Kuan Yan,Li Shen,Xiaobing Wang,Youxuan Xu,Genye He,Yun Wu,Jianghai Lu,Zhiyong Yang,Feifei Feng. (2014-03-25) Quantitative analysis of glycerol levels in human urine by liquid chromatography-tandem mass spectrometry.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 957 (30-35). [PMID:24657408] |
| 19. Xueyan Zheng,Richard D Gandour,Kevin J Edgar. (2014-07-20) Remarkably regioselective deacylation of cellulose esters using tetraalkylammonium salts of the strongly basic hydroxide ion.. Carbohydrate polymers, 111 (25-32). [PMID:25037325] |
| 20. Laurent Imbert,Elodie Saussereau,Christian Lacroix. (2014-09-05) Analysis of eight glycols in serum using LC-ESI-MS-MS.. Journal of analytical toxicology, 38 ((9)): (676-680). [PMID:25187402] |
| 21. Sufang Wang,Bin Wan,Lianying Zhang,Yu Yang,Liang-Hong Guo. (2014-09-30) In vitro inhibition of lysine decarboxylase activity by organophosphate esters.. Biochemical pharmacology, 92 ((3)): (506-516). [PMID:25264276] |
| 22. Andreas Bornø,Lene Foged,Gerrit van Hall. (2014-10-11) Glucose and glycerol concentrations and their tracer enrichment measurements using liquid chromatography tandem mass spectrometry.. Journal of mass spectrometry : JMS, 49 ((10)): (980-988). [PMID:25303387] |
| 23. Fumio Kondo,Masahiko Tachi,Masahiko Gosho,Minoru Fukayama,Kazuhiro Yoshikawa,Shoshiro Okada. (2015-01-31) Changes in hypothalamic neurotransmitter and prostanoid levels in response to NMDA, CRF, and GLP-1 stimulation.. Analytical and bioanalytical chemistry, 407 ((18)): (5261-5272). [PMID:25633219] |
| 24. Fernando Montañés,Paul Rose,Stephen Tallon,Rahau Shirazi. (2015-09-29) Separation of derivatized glucoside anomers using supercritical fluid chromatography.. Journal of chromatography. A, 1418 (218-223). [PMID:26411481] |
| 25. Brianna H Hughes,L Brian Perkins,Tom C Yang,Denise I Skonberg. (2015-10-17) Impact of post-rigor high pressure processing on the physicochemical and microbial shelf-life of cultured red abalone (Haliotis rufescens).. Food chemistry, 194 (487-494). [PMID:26471583] |
| 26. J Báscuas,L García-Río,J R Leis. (2004-04-06) Cyclodextrin effect on solvolysis of substituted benzoyl chlorides.. Organic & biomolecular chemistry, 2 ((8)): (1186-1193). [PMID:15064797] |
| 27. Russell J Cox,Dougal J Ritson,Thomas A Dane,John Berge,Jonathan P H Charmant,Anob Kantacha. (2005-02-19) Room temperature palladium catalysed coupling of acyl chlorides with terminal alkynes.. Chemical communications (Cambridge, England), (8) ((8)): (1037-1039). [PMID:15719108] |
| 28. Hongxia Li,Jun Dong,Wenxiang Chen,Shu Wang,Hanbang Guo,Yong Man,Peisheng Mo,Jianzhai Li. (2006-06-22) Measurement of serum total glycerides and free glycerol by high-performance liquid chromatography.. Journal of lipid research, 47 ((9)): (2089-2096). [PMID:16788212] |
| 29. Lijun Tang,Shufen Zhang,Jinzong Yang,Wentao Gao,Jian Cui,Tianyu Zhuang. (2007-11-17) A novel approach to the synthesis of 6-amino-7-hydroxy-flavone.. Molecules (Basel, Switzerland), 9 ((10)): (842-848). [PMID:18007484] |
| 30. Ozgül Ozdestan,Ali Uren. (2009-04-14) A method for benzoyl chloride derivatization of biogenic amines for high performance liquid chromatography.. Talanta, 78 ((4-5)): (1321-1326). [PMID:19362195] |
| 31. Pramod Kumar Verma,Abhinanadan Makhal,Rajib Kumar Mitra,Samir Kumar Pal. (2009-09-24) Role of solvation dynamics in the kinetics of solvolysis reactions in microreactors.. Physical chemistry chemical physics : PCCP, 11 ((38)): (8467-8476). [PMID:19774277] |
| 32. Heng Li,Lantao Liu,Zitao Wang,Fei Zhao,Shaoguang Zhang,Wen-Xiong Zhang,Zhenfeng Xi. (2011-05-28) Iterative dianion relay along the ring: formation of gem-bis(trimethylsilyl) cyclopentenones from 2,5-bis(trimethylsilyl) oxy-cyclopentadienyl dianions and acid chlorides.. Chemistry (Weinheim an der Bergstrasse, Germany), 17 ((27)): (7399-7403). [PMID:21618298] |
| 33. Peng Song,Omar S Mabrouk,Neil D Hershey,Robert T Kennedy. (2011-11-29) In vivo neurochemical monitoring using benzoyl chloride derivatization and liquid chromatography-mass spectrometry.. Analytical chemistry, 84 ((1)): (412-419). [PMID:22118158] |
| 34. Brandon C Wilcock,Brice E Uno,Gretchen L Bromann,Matthew J Clark,Thomas M Anderson,Martin D Burke. (2012-11-24) Electronic tuning of site-selectivity.. Nature chemistry, 4 ((12)): (996-1003). [PMID:23174979] |
| 35. Vutukuri Prakash Reddy,Renhua Qiu,Takanori Iwasaki,Nobuaki Kambe. (2015-05-27) Nickel-catalyzed synthesis of diarylsulfides and sulfones via C-H bond functionalization of arylamides.. Organic & biomolecular chemistry, 13 ((24)): (6803-6813). [PMID:26006765] |