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Berberine - 99%, high purity , CAS No.2086-83-1, Inhibitor of CYP2D6
Basic Description Synonyms berberine|2086-83-1|Umbellatine|Berberin|Berbericine|Majarine|Thalsine|Umbellatin|Berberone|0I8Y3P32UF|CHEBI:16118|EINECS 218-229-1|BRN 3570374|UNII-0I8Y3P32UF|Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-|DTXSID9043857|9,10-D Specifications & Purity 99% Storage Temp Protected from light,Store at -20°C Shipped In Ice chest + Ice pads Grade Moligand™ Action Type INHIBITOR Mechanism of action Inhibitor of CYP2D6 Product Description Product Describtion:
Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine (Natural Yellow 18) induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine (Natural Yellow 18) has antineoplastic properties.
Names and Identifiers Pubchem Sid 488179694 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488179694 IUPAC Name 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene INCHI InChI=1S/C20H18NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-10H,5-6,11H2,1-2H3/q+1 InChi Key YBHILYKTIRIUTE-UHFFFAOYSA-N Canonical SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC Isomeric SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC Alternate CAS 2086-83-1 PubChem CID 2353 MeSH Entry Terms Berberine;Umbellatine Molecular Weight 336.37
Chemical and Physical Properties Solubility Solubility (25°C) In vitro DMSO: 22.5 mg/mL (66.89 mM); Ethanol: 5 mg/mL (14.86 mM); Water: 1 mg/mL (2.97 mM); Sensitivity Moisture Sensitive；Light Sensitive
Safety and Hazards(GHS) Pictogram(s) GHS06 , GHS07 Signal Danger Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H301: Toxic if swallowed
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
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G2431157
