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SKU | Size | Availability | Price | Qty |
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B275720-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $147.90 | |
B275720-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $669.90 |
Cell-permeable derivative of Bestatin ( ab141417 ); neutral aminopeptidase inhibitor.
Synonyms | Bestatin Methyl Ester | BDBM50251279 | (S)-methyl 2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoate | Methyl Bestatin | DTXSID20432965 | SCHEMBL9574604 | AT39119 | methyl (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methy |
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Specifications & Purity | ≥97% |
Biochemical and Physiological Mechanisms | Cell-permeable derivative of Bestatin. Displays slightly stronger inhibition of neutral aminopeptidase than Bestatin but has much weaker activity against basic aminopeptidase. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at +4°C. The product can be stored for up to 12 months. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Bcr/Abl fusion protein inhibitor | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | ||
Bcr/Abl fusion protein inhibitor | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | ||
Bcr/Abl fusion protein | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | FDA: [1] | |
Bcr/Abl fusion protein | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | FDA: [1] | |
Bcr/Abl fusion protein | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | FDA: [1] | |
Bcr/Abl fusion protein | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | FDA: [1] | |
Bcr/Abl fusion protein inhibitor | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | PubMed: [1] | |
Bcr/Abl fusion protein inhibitor | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | Other: [1] | |
Bcr/Abl fusion protein inhibitor | INHIBITOR | ALA2096618 | Bcr/Abl fusion protein | CHIMERIC PROTEIN | Homo sapiens | FDA: [1] |
IUPAC Name | methyl (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoate |
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INCHI | InChI=1S/C17H26N2O4/c1-11(2)9-14(17(22)23-3)19-16(21)15(20)13(18)10-12-7-5-4-6-8-12/h4-8,11,13-15,20H,9-10,18H2,1-3H3,(H,19,21)/t13-,14+,15+/m1/s1 |
InChi Key | WGNKTWBIPBOGLO-ILXRZTDVSA-N |
Canonical SMILES | CC(C)CC(C(=O)OC)NC(=O)C(C(CC1=CC=CC=C1)N)O |
Isomeric SMILES | CC(C)C[C@@H](C(=O)OC)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O |
PubChem CID | 9927170 |
Molecular Weight | 322.4 |
Solubility | Soluble in DMSO |
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