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Bestatin methyl ester - ≥97%, high purity , CAS No.65322-89-6

  • ≥97%
Item Number
B275720
Grouped product items
SKUSizeAvailabilityPrice Qty
B275720-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$147.90
B275720-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$669.90

Cell-permeable derivative of Bestatin ( ab141417 ); neutral aminopeptidase inhibitor.

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Basic Description

SynonymsBestatin Methyl Ester | BDBM50251279 | (S)-methyl 2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoate | Methyl Bestatin | DTXSID20432965 | SCHEMBL9574604 | AT39119 | methyl (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methy
Specifications & Purity≥97%
Biochemical and Physiological MechanismsCell-permeable derivative of Bestatin. Displays slightly stronger inhibition of neutral aminopeptidase than Bestatin but has much weaker activity against basic aminopeptidase.
Storage TempStore at 2-8°C
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. The product can be stored for up to 12 months.

Associated Targets(Human)

BIRC2 Tchem Baculoviral IAP repeat-containing protein 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
BIRC3 Tchem Baculoviral IAP repeat-containing protein 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HT-1080 (3966 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IMR-32 (1082 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BIRC3 Tchem Baculoviral IAP repeat-containing protein 3 (320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BIRC2 Tchem Baculoviral IAP repeat-containing protein 2 (984 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABL1 Tclin Bcr/Abl fusion protein (1667 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRABP2 Tchem Complex of retinoic acid binding (CRABPII) and inhibitor of apoptosis (cIAP1) proteins (18 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences
Bcr/Abl fusion protein inhibitorINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

DailyMed: [1]


PubMed: [1]


Bcr/Abl fusion protein inhibitorINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

PubMed: [1] , [2] , [3]


Bcr/Abl fusion proteinINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

FDA: [1]


Bcr/Abl fusion proteinINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

FDA: [1]


Bcr/Abl fusion proteinINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

FDA: [1]


Bcr/Abl fusion proteinINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

FDA: [1]


Bcr/Abl fusion protein inhibitorINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

PubMed: [1]


Bcr/Abl fusion protein inhibitorINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

Other: [1]


Bcr/Abl fusion protein inhibitorINHIBITORALA2096618Bcr/Abl fusion proteinCHIMERIC PROTEINHomo sapiens

FDA: [1]


Names and Identifiers

IUPAC Name methyl (2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-4-methylpentanoate
INCHI InChI=1S/C17H26N2O4/c1-11(2)9-14(17(22)23-3)19-16(21)15(20)13(18)10-12-7-5-4-6-8-12/h4-8,11,13-15,20H,9-10,18H2,1-3H3,(H,19,21)/t13-,14+,15+/m1/s1
InChi Key WGNKTWBIPBOGLO-ILXRZTDVSA-N
Canonical SMILES CC(C)CC(C(=O)OC)NC(=O)C(C(CC1=CC=CC=C1)N)O
Isomeric SMILES CC(C)C[C@@H](C(=O)OC)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O
PubChem CID 9927170
Molecular Weight 322.4

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
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Chemical and Physical Properties

SolubilitySoluble in DMSO

Related Documents

Solution Calculators