![Bis[rhodium(α,α,α',α'-tetramethyl-1,3-benzenedipropionic Acid)]](https://media-prod.aladdinsci.com/media/catalog/product/cache/515ce11dbf2c7bc125424616eb49ad88/B/1/B152255.png)
Determine the necessary mass, volume, or concentration for preparing a solution.
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Basic Description
| Synonyms | BETAMETHASONE DIPROPIONATE|Diprolene|Diprosone|Alphatrex|Maxivate|Diprolene AF|5593-20-4|Diproderm|Psorion|Rinderon DP|Diprosis|Betamethasone 17,21-dipropionate|Diprospan|Sch 11460|Sernivo|Sch-11460|Rinderon-DP|EINECS 227-005-2|S-3440|BRN 3638108|Betameth |
|---|---|
| Specifications & Purity | ≥97% |
| Shipped In | Normal |
| Action Type | AGONIST |
| Mechanism of action | Glucocorticoid receptor agonist |
| Product Description | Betamethasone 17,21-dipropionate is a glucocorticoid with anti-inflammatory and immunosuppressive activity. |
Product Properties
| ALogP | 3.6 |
|---|
Associated Targets
CXCL14 Tbio C-X-C motif chemokine 14 0 Activities
CNR1 Tclin Cannabinoid receptor 1 0 Activities
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DRD1 Tclin D(1A) dopamine receptor 0 Activities
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DRD2 Tclin D(2) dopamine receptor 0 Activities
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ESR1 Tclin Estrogen receptor 0 Activities
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GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities
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NR3C1 Tclin Glucocorticoid receptor 0 Activities
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AVPR1A Tclin Vasopressin V1a receptor 0 Activities
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HRH3 Tclin Histamine H3 receptor 0 Activities
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HDAC6 Tclin Histone deacetylase 6 0 Activities
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HRH1 Tclin Histamine H1 receptor 0 Activities
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SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities
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SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities
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SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities
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PGR Tclin Progesterone receptor 0 Activities
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PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities
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PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities
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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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CACNA1C Tclin Voltage-dependent L-type calcium channel subunit alpha-1C 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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DRD3 Tclin D(3) dopamine receptor 0 Activities
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CHRM3 Tclin Muscarinic acetylcholine receptor M3 0 Activities
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ADRA2B Tclin Alpha-2B adrenergic receptor 0 Activities
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CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities
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ADRA2C Tclin Alpha-2C adrenergic receptor 0 Activities
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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase 0 Activities
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HTR2A Tclin 5-hydroxytryptamine receptor 2A 0 Activities
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ADORA2A Tclin Adenosine receptor A2a 0 Activities
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CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities
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ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities
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ADRB1 Tclin Beta-1 adrenergic receptor 0 Activities
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ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities
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AR Tclin Androgen receptor 0 Activities
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MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities
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HTR2C Tclin 5-hydroxytryptamine receptor 2C 0 Activities
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ADORA1 Tclin Adenosine receptor A1 0 Activities
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HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ADORA3 Tchem Adenosine receptor A3 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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HTR3A Tclin 5-hydroxytryptamine receptor 3A 0 Activities
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HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities
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TBXA2R Tclin Thromboxane A2 receptor 0 Activities
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EDNRA Tclin Endothelin-1 receptor 0 Activities
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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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OPRD1 Tclin Delta-type opioid receptor 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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OPRK1 Tclin Kappa-type opioid receptor 0 Activities
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OPRM1 Tclin Mu-type opioid receptor 0 Activities
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MLNR Tchem Motilin receptor 0 Activities
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Names and Identifiers
| Pubchem Sid | 488182722 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488182722 |
| IUPAC Name | [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate |
| INCHI | InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1 |
| InChi Key | CIWBQSYVNNPZIQ-XYWKZLDCSA-N |
| Canonical SMILES | CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CC |
| Isomeric SMILES | CCC(=O)OCC(=O)[C@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)OC(=O)CC |
| WGK Germany | 2 |
| RTECS | TU4058000 |
| PubChem CID | 21800 |
| Molecular Weight | 504.59 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2314102 | Certificate of Analysis | Sep 23, 2022 | B123297 |
| L2213422 | Certificate of Analysis | Sep 23, 2022 | B123297 |
| H1408111 | Certificate of Analysis | Jun 08, 2022 | B123297 |
| H1408110 | Certificate of Analysis | Jun 08, 2022 | B123297 |
| C1426078 | Certificate of Analysis | Jan 11, 2022 | B123297 |
Chemical and Physical Properties
| Solubility | 50 mg/ml in chloroform |
|---|---|
| Melt Point(°C) | 175.0°C-179.0°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS06, GHS08, GHS09 |
|---|---|
| Signal | Danger |
| Hazard Statements | H410:Very toxic to aquatic life with long lasting effects H330:Fatal if inhaled H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child H361:Suspected of damaging fertility or the unborn child |
| Precautionary Statements | P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P391:Collect spillage. P320:Specific treatment is urgent (see ... on this label). P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell. |
| WGK Germany | 2 |
| RTECS | TU4058000 |
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