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BGC 20-761 - ≥98%(HPLC), high purity , CAS No.17375-63-2, Antagonist of 5-HT 1A receptor;Antagonist of 5-HT 1D receptor;Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 5A receptor;Antagonist of 5-HT 6 receptor;Antagonist of 5-HT 7 receptor

Moligand™
≥98%(HPLC)

CAS#: 17375-63-2
Formula: C₁₉H₂₂N₂O
Molecular Weight: 294.39
PubChem CID: 6918515

Item Number

B288458

Grouped product items
SKU	Size	Availability	Price	Qty
B288458-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$175.90

High affinity 5-HT6antagonist

View related series

5-HT1A receptor Antagonist 5-HT1D receptor Antagonist 5-HT2A receptor Antagonist 5-HT2C receptor Antagonist 5-HT5A receptor Antagonist 5-HT6 receptor Antagonist 5-HT7 receptor Antagonist

Basic Description

Synonyms	17375-63-2\|BGC 20-761\|BGC-20-761\|MPDT\|1H-Indole-3-ethanamine, 5-methoxy-N,N-dimethyl-2-phenyl-\|BGC20-761\|2-(5-methoxy-2-phenyl-1H-indol-3-yl)-N,N-dimethylethanamine\|5-Methoxy-N,N-dimethyl-2-phenyl-1H-indole-3-ethanamine\|6G5F6ESV5I\|CHEMBL7318\|Indole, 3-(2-
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Selective, high affinity 5-HT6antagonist (Ki= 20 nM). Reverses the amnesic effects ofscopolamine and enhances memory consolidation in a rat model.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of 5-HT 1A receptor;Antagonist of 5-HT 1D receptor;Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 2C receptor;Antagonist of 5-HT 5A receptor;Antagonist of 5-HT 6 receptor;Antagonist of 5-HT 7 receptor

Associated Targets

SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities

Discover Target: SLC6A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities

Discover Target: SLC6A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR5A Tchem 5-hydroxytryptamine receptor 5A 1 Activities

Discover Target: HTR5A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin 5-hydroxytryptamine receptor 2A 1 Activities

Discover Target: HTR2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1E Tchem 5-hydroxytryptamine receptor 1E 0 Activities

Discover Target: HTR1E

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR7 Tclin 5-hydroxytryptamine receptor 7 1 Activities

Discover Target: HTR7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1D Tclin 5-hydroxytryptamine receptor 1D 1 Activities

Discover Target: HTR1D

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2C Tclin 5-hydroxytryptamine receptor 2C 1 Activities

Discover Target: HTR2C

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR1A Tclin 5-hydroxytryptamine receptor 1A 1 Activities

Discover Target: HTR1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR6 Tchem 5-hydroxytryptamine receptor 6 8 Activities

Discover Target: HTR6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-(5-methoxy-2-phenyl-1H-indol-3-yl)-N,N-dimethylethanamine
INCHI	InChI=1S/C19H22N2O/c1-21(2)12-11-16-17-13-15(22-3)9-10-18(17)20-19(16)14-7-5-4-6-8-14/h4-10,13,20H,11-12H2,1-3H3
InChi Key	VSGPGYWZVPDDSK-UHFFFAOYSA-N
Canonical SMILES	CN(C)CCC1=C(NC2=C1C=C(C=C2)OC)C3=CC=CC=C3
Isomeric SMILES	CN(C)CCC1=C(NC2=C1C=C(C=C2)OC)C3=CC=CC=C3
PubChem CID	6918515
Molecular Weight	294.39

PubChem CID

ChEMBL Ligand

CAS Registry No.

GPCRdb Ligand

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