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BI-1015550 - 98%, high purity , CAS No.1423719-30-5, Inhibitor of phosphodiesterase 4A;Inhibitor of phosphodiesterase 4B;Inhibitor of phosphodiesterase 4D

  • Moligand™
  • ≥98%
Item Number
B608042
Grouped product items
SKUSizeAvailabilityPrice Qty
B608042-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
B608042-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
B608042-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$169.90
B608042-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$349.90
B608042-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$559.90

Basic Description

SynonymsBI 1015550|BI-1015550|1423719-30-5|I5DGT51IB8|GTPL12518|EX-A7747|BI1015550|HY-153192|CS-0654251|[1-[[(5R)-2-[4-(5-chloropyrimidin-2-yl)piperidin-1-yl]-5-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]amino]cyclobutyl]methanol|CYCLOBUTANEMETHANOL, 1-(((5R)-2-(
Specifications & Purity98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of phosphodiesterase 4A;Inhibitor of phosphodiesterase 4B;Inhibitor of phosphodiesterase 4D

Associated Targets

PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE4A Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PDE4B Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name [1-[[(5R)-2-[4-(5-chloropyrimidin-2-yl)piperidin-1-yl]-5-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]amino]cyclobutyl]methanol
INCHI InChI=1S/C20H25ClN6O2S/c21-14-10-22-17(23-11-14)13-2-7-27(8-3-13)19-24-15-4-9-30(29)16(15)18(25-19)26-20(12-28)5-1-6-20/h10-11,13,28H,1-9,12H2,(H,24,25,26)/t30-/m1/s1
InChi Key UHYCLWAANUGUMN-SSEXGKCCSA-N
Canonical SMILES OCC1(CCC1)NC2=NC(=NC3=C2[S@](=O)CC3)N4CCC(CC4)C5=NC=C(Cl)C=N5
Isomeric SMILES C1CC(C1)(CO)NC2=NC(=NC3=C2[S@](=O)CC3)N4CCC(CC4)C5=NC=C(C=N5)Cl
PubChem CID 166177189
Molecular Weight 448.97

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
B2418005Certificate of AnalysisJan 05, 2024 B608042
B2418006Certificate of AnalysisJan 05, 2024 B608042
B2418052Certificate of AnalysisJan 05, 2024 B608042
B2418053Certificate of AnalysisJan 05, 2024 B608042
B2418056Certificate of AnalysisJan 05, 2024 B608042
B2418058Certificate of AnalysisJan 05, 2024 B608042
B2418059Certificate of AnalysisJan 05, 2024 B608042
B2418060Certificate of AnalysisJan 05, 2024 B608042
B2418061Certificate of AnalysisJan 05, 2024 B608042
B2418062Certificate of AnalysisJan 05, 2024 B608042

Related Documents

References

1. Herrmann FE, Hesslinger C, Wollin L, Nickolaus P.  (2022)  BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis..  Front Pharmacol,  13  (3): (838449).  [PMID:35517783]

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