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BI-7273 - 10mM in DMSO, high purity , CAS No.1883429-21-7
Epigenetic Reader Domain Inhibitors
Basic Description Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms BI-7273 is a potent, selective, and cell-permeable BRD9 BD inhibitor with IC50s of 19 nM and 117 nM for BRD9 and BRD7 respectively in alpha assay. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description Information
BI-7273 BI-7273 is a potent, selective, and cell-permeable BRD9 BD inhibitor with IC50s of 19 nM and 117 nM for BRD9 and BRD7 respectively in alpha assay.
Targets
BRD9 (Cell-free assay); BRD7 (Cell-free assay) 19 nM; 117 nM
Product Properties ALogP 1.301 Rotatable Bond 5
Names and Identifiers IUPAC Name 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridin-1-one INCHI InChI=1S/C20H23N3O3/c1-22(2)11-17-18(25-4)8-13(9-19(17)26-5)16-12-23(3)20(24)15-10-21-7-6-14(15)16/h6-10,12H,11H2,1-5H3 InChi Key RBUYFHLQNPJMQM-UHFFFAOYSA-N Canonical SMILES CN1C=C(C2=C(C1=O)C=NC=C2)C3=CC(=C(C(=C3)OC)CN(C)C)OC Isomeric SMILES CN1C=C(C2=C(C1=O)C=NC=C2)C3=CC(=C(C(=C3)OC)CN(C)C)OC PubChem CID 118796358 Molecular Weight 353.41
Chemical and Physical Properties DMSO(mg / mL) Max Solubility 70 DMSO(mM) Max Solubility 198.07023 Water(mg / mL) Max Solubility ＜1
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