Bicinchoninic acid disodium salt - 98%, high purity , CAS No.979-88-4

  • ≥98%
Item Number
B107658
Grouped product items
SKUSizeAvailabilityPrice Qty
B107658-1g
1g
In stock
$29.90
B107658-5g
5g
In stock
$99.90
B107658-25g
25g
In stock
$349.90
B107658-100g
100g
In stock
$979.90

Protein concentration determination reagent.

Basic Description

SynonymsBCA | B5838 | BCADisodium | B4509 | AKOS015951447 | Bicinchoninic Acid Disodium Salt [for Protein Research] | DISODIUM [2,2'-BIQUINOLINE]-4,4'-DICARBOXYLATE | Disodium 2,2a?biquinoline-4,4a?dicarboxylate | disodium;2-(4-carboxylatoquinolin-2-yl)quinoline-
Specifications & Purity≥98%
Biochemical and Physiological MechanismsBicinchoninic acid is used for the determination of protein concentration. It is responsible for the making of intense purple complex with cuprous ion (Cu+), in presence of alkaline conditions. The amount of Cu+ is in relation with the protein concentrati
Storage TempStore at 2-8°C
Shipped InWet ice
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

For the determination of protein concentration. 

• Bicinchoninic acid disodium salt hydrate has been used to monitor the levels of reducing sugars, thereby helping in the detection of chitinases.

• It has also been used to determine the amount of cellulose reducing ends (micromoles/g cellulose). 

• It has been used for determining protein concentration.

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488188374
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488188374
IUPAC Name disodium;2-(4-carboxylatoquinolin-2-yl)quinoline-4-carboxylate
INCHI InChI=1S/C20H12N2O4.2Na/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;/h1-10H,(H,23,24)(H,25,26);;/q;2*+1/p-2
InChi Key AUPXFICLXPLHBB-UHFFFAOYSA-L
Canonical SMILES O.[Na+].[Na+].[O-]C(=O)c1cc(nc2ccccc12)-c3cc(C([O-])=O)c4ccccc4n3
Isomeric SMILES C1=CC=C2C(=C1)C(=CC(=N2)C3=NC4=CC=CC=C4C(=C3)C(=O)[O-])C(=O)[O-].[Na+].[Na+]
PubChem CID 164763
Molecular Weight 388.28 (anhydrous basis)

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

40 results found

Lot NumberCertificate TypeDateItem
K2419263Certificate of AnalysisNov 06, 2024 B107658
K2419227Certificate of AnalysisNov 06, 2024 B107658
K2419226Certificate of AnalysisNov 06, 2024 B107658
J2423552Certificate of AnalysisOct 10, 2024 B107658
J2423546Certificate of AnalysisOct 10, 2024 B107658
J2423545Certificate of AnalysisOct 10, 2024 B107658
I2403172Certificate of AnalysisAug 23, 2024 B107658
I2403180Certificate of AnalysisAug 23, 2024 B107658
C2430035Certificate of AnalysisMar 18, 2024 B107658
C2430036Certificate of AnalysisMar 18, 2024 B107658
D2407119Certificate of AnalysisMar 14, 2024 B107658
D2407118Certificate of AnalysisMar 14, 2024 B107658
H2407041Certificate of AnalysisMar 14, 2024 B107658
D2411267Certificate of AnalysisMar 14, 2024 B107658
D2411266Certificate of AnalysisMar 14, 2024 B107658
D2407121Certificate of AnalysisMar 14, 2024 B107658
L2321485Certificate of AnalysisDec 12, 2023 B107658
L2321486Certificate of AnalysisDec 12, 2023 B107658
L2321487Certificate of AnalysisDec 12, 2023 B107658
I2321171Certificate of AnalysisSep 09, 2023 B107658
I2321172Certificate of AnalysisSep 09, 2023 B107658
I2321173Certificate of AnalysisSep 09, 2023 B107658
I2321191Certificate of AnalysisSep 09, 2023 B107658
D2319303Certificate of AnalysisApr 08, 2023 B107658
D2319272Certificate of AnalysisApr 08, 2023 B107658
D2319278Certificate of AnalysisApr 08, 2023 B107658
D2319291Certificate of AnalysisApr 08, 2023 B107658
D2319299Certificate of AnalysisApr 08, 2023 B107658
D2319308Certificate of AnalysisApr 08, 2023 B107658
D2319270Certificate of AnalysisApr 08, 2023 B107658
D2319269Certificate of AnalysisApr 08, 2023 B107658
K2215615Certificate of AnalysisAug 18, 2022 B107658
K2215616Certificate of AnalysisAug 18, 2022 B107658
K2215617Certificate of AnalysisAug 18, 2022 B107658
K2215618Certificate of AnalysisAug 18, 2022 B107658
G2227663Certificate of AnalysisJul 12, 2022 B107658
G2227662Certificate of AnalysisJul 12, 2022 B107658
G2227664Certificate of AnalysisJul 12, 2022 B107658
C2222366Certificate of AnalysisFeb 18, 2022 B107658
C2222293Certificate of AnalysisFeb 18, 2022 B107658

Show more⌵

Chemical and Physical Properties

SolubilitySoluble in water. 0.5% sodium bicarbonate: 50 mg/mL
Sensitivityheat sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

Precautionary Statements

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P264:Wash hands [and …] thoroughly after handling.

P337+P313:IF eye irritation persists: Get medical advice/attention.

P332+P313:IF SKIN irritation occurs: Get medical advice/attention.

Related Documents

Citations of This Product

1. Leying Zha, Lei Ning, Zeyuan Sun, Lixin Song, Pingfan Du, Jie Xiong.  (2023)  A Multifunctional Hydrogen Bond Bridge Interface to Achieving Efficient and Stable Perovskite Solar Cells.  Advanced Optical Materials,    (15): (2302163).  [PMID:12200376] [10.1002/adom.202302163]
2. Kuanrong Zhai, Bingjian Zhang, Longguan Zhu.  (2023)  A new proposed semi-quantitative method for the organic additives analysis in traditional lime mortar.  JOURNAL OF CULTURAL HERITAGE,  62  (284).  [PMID:] [10.1016/j.culher.2023.06.003]
3. Junqin Li, Wenhua Yi, Yuze Luo, Ke Yang, Lidan He, Caiyun Xu, Le Deng, Dinggeng He.  (2023)  GSH-depleting and H2O2-self-supplying hybrid nanozymes for intensive catalytic antibacterial therapy by photothermal-augmented co-catalysis.  Acta Biomaterialia,  155  (588).  [PMID:36328125] [10.1016/j.actbio.2022.10.050]
4. Siyu Jin, Dongru Li, Xingjia Feng, Guoqi Fu.  (2022)  Synthesis of carbon dots-based surface protein-imprinted nanoparticles via sandwich-structured template pre-assemble and post-imprinting modification for enhanced fluorescence detection.  MICROCHEMICAL JOURNAL,  180  (107611).  [PMID:] [10.1016/j.microc.2022.107611]

References

1. Bao Z et al..  (2021)  rTMS alleviates AD-induced cognitive impairment by inhibitng apoptosis in SAMP8 mouse..  Aging (Albany NY),  13  (24): (26034-26045).  [PMID:34965216]
2. Li T et al..  (2020)  The antitumor effect of miR-448 in epithelial ovarian cancer..  Transl Cancer Res,  (8): (4922-4930).  [PMID:35117854]
3. Li G et al..  (2019)  Tumor suppressor function of miR-129-5p in lung cancer..  Oncol Lett,  17  (6): (5777-5783).  [PMID:31186804]
4. Leying Zha, Lei Ning, Zeyuan Sun, Lixin Song, Pingfan Du, Jie Xiong.  (2023)  A Multifunctional Hydrogen Bond Bridge Interface to Achieving Efficient and Stable Perovskite Solar Cells.  Advanced Optical Materials,    (15): (2302163).  [PMID:12200376] [10.1002/adom.202302163]
5. Kuanrong Zhai, Bingjian Zhang, Longguan Zhu.  (2023)  A new proposed semi-quantitative method for the organic additives analysis in traditional lime mortar.  JOURNAL OF CULTURAL HERITAGE,  62  (284).  [PMID:] [10.1016/j.culher.2023.06.003]
6. Junqin Li, Wenhua Yi, Yuze Luo, Ke Yang, Lidan He, Caiyun Xu, Le Deng, Dinggeng He.  (2023)  GSH-depleting and H2O2-self-supplying hybrid nanozymes for intensive catalytic antibacterial therapy by photothermal-augmented co-catalysis.  Acta Biomaterialia,  155  (588).  [PMID:36328125] [10.1016/j.actbio.2022.10.050]
7. Siyu Jin, Dongru Li, Xingjia Feng, Guoqi Fu.  (2022)  Synthesis of carbon dots-based surface protein-imprinted nanoparticles via sandwich-structured template pre-assemble and post-imprinting modification for enhanced fluorescence detection.  MICROCHEMICAL JOURNAL,  180  (107611).  [PMID:] [10.1016/j.microc.2022.107611]

Solution Calculators