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Bimatoprost - 10mM in DMSO, high purity , CAS No.155206-00-1
Basic Description Synonyms Bimatoprost|155206-00-1|Lumigan|Latisse|AGN 192024|Prostamide|bimatoprostum|AGN-192024|UNII-QXS94885MZ|DURYSTA|QXS94885MZ|CHEBI:51230|LS-181817|(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide| Specifications & Purity Moligand™, 10mM in DMSO Biochemical and Physiological Mechanisms Bimatoprost is converted by an amidase enzymatic activity in bovine and human cornea models to yield the corresponding free acid, 17-phenyl trinor PGF2α, a potent PGF2αR agonist. In human and animal models of glaucoma, FP receptor agonist activity corresp Storage Temp Protected from light,Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description The precursor to a potent PGF2αR agonist.
Names and Identifiers IUPAC Name (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide INCHI InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20-,21+,22+,23-,24+/m0/s1 InChi Key AQOKCDNYWBIDND-FTOWTWDKSA-N Canonical SMILES CCNC(=O)CCCC=CCC1C(CC(C1C=CC(CCC2=CC=CC=C2)O)O)O Isomeric SMILES CCNC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](CCC2=CC=CC=C2)O)O)O WGK Germany 3 PubChem CID 5311027 Molecular Weight 415.57
Chemical and Physical Properties Sensitivity Air Sensitive,Heat Sensitive Specific Rotation[α] 35° (C=1,MeOH) Melt Point(°C) 75 °C
Safety and Hazards(GHS) Pictogram(s) GHS08 , GHS07 Signal Danger Hazard Statements H319: Causes serious eye irritation
H302: Harmful if swallowed
H312: Harmful in contact with skin
H360: May damage fertility or the unborn child
H340: May cause genetic defects
H361: Suspected of damaging fertility or the unborn child
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P281: Use personal protective equipment as required.
P270: Do not eat, drink or smoke when using this product.
P362+P364: Take off contaminated clothing and wash it before reuse.
P330: Rinse mouth.
P203: Obtain, read and follow all safety instructions before use.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P301+P317: IF SWALLOWED: Get medical help.
P318: if exposed or concerned, get medical advice.
P317: Get emergency medical help.
P337+P317: If eye irritation persists: Get medical help.
WGK Germany 3 Merck Index 1221
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