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BIO-013077-01 - 98%, high purity , CAS No.746667-48-1

  • ≥98%
Item Number
B650439
Grouped product items
SKUSizeAvailabilityPrice Qty
B650439-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$90.90
B650439-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$190.90
B650439-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$290.90
B650439-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$580.90
B650439-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$850.90
View related series
TGF-beta/Smad TGF-β Receptor

Basic Description

Synonyms746667-48-1|6-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoxaline|BIO-013077-01|6-[3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoxaline|6-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoxaline|SCHEMBL4008166|DTXSID00440482|BCP30129|EX-A3237|ZB0034|AKOS01
Specifications & Purity98%
Storage TempStore at -20°C
Shipped InDry ice
Product Description

BIO-013077-01 is a pyrazole TGF-β inhibitor.

In Vitro

A wide range of cellular functions such as cell proliferation, differentiation, adhesion, migration, and apoptosis are regulated by TGF-β superfamily members. The TGF-βs include the three major TGF-β isoforms, TGF-β1, TGF-β2, and TGF-β3 which are expressed in mammals. TGF-β transduces signals through a complex of two related but structurally and functionally distinct serine/threonine kinase receptors, termed type 1 and type II. Deregulation of TGF-β signaling has been also implicated in various human diseases including cancer, pancreatic diseases, and hematological malignancies. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Names and Identifiers

IUPAC Name 6-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoxaline
INCHI InChI=1S/C17H13N5/c1-11-3-2-4-15(21-11)17-13(10-20-22-17)12-5-6-14-16(9-12)19-8-7-18-14/h2-10H,1H3,(H,20,22)
InChi Key VXJLYXCHOKEODY-UHFFFAOYSA-N
Canonical SMILES CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC4=NC=CN=C4C=C3
Isomeric SMILES CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC4=NC=CN=C4C=C3
Alternate CAS 746667-48-1
PubChem CID 10469294
Molecular Weight 287.32

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : 100 mg/mL (348.04 mM; Need ultrasonic)

Related Documents

Solution Calculators